宁波泰斯拓生物

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浙江省宁波市镇海区庄市街道兴庄路9号创e慧谷42号楼B幢401室
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Y-156

货号 TS157070
中文名称 null
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产品简介
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产品名称: Y-156
商品货号: TS157070
Designations: Y-156
Species: Homo sapiens, human
Vector:
Construct size (kb): 7.199999809265137
Insert:
DNA: genomic
Insert lengths(kb): 4.400000095367432
Tissue: 49,XXXXY cell line
Gene product: DNA Segment DYZ*2
Insert Size (kb): 4.400
Biosafety Level: 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Shipping Information: Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug)
Comments:
Restriction digests of the clone give the following sizes (kb): AvaI--2.7, 2.4, 2.1; BamHI--7.2; EcoRI--4.4, 2.8; NotI--uncut; HindIII--4.4, 2.8.
This probe detects a Y-specific 4.4 kb HindIII fragment which has about 10 copies in normal males. It also detects 6 fainter Y-specific bands ranging from 2 to 15 kb. The copy number of the 4.4 kb fragment may be reduced in gonadal dysgenesis.
References:

Muller U, et al. Moderately repeated DNA sequences specific for the short arm of the human Y chromosome are present in XX males and reduced in copy number in an XY female. Nucleic Acids Res. 14: 1325-1340, 1986. PubMed: 3951989

Gaunt SJ. Mapping of testis-determining locus on Yp by the molecular genetic analysis of XX males and XY females. Development 101: 51-58, 1987. PubMed: 88211484