| 产品名称: | pJA110 |
|---|---|
| 商品货号: | TS158374 |
| Designations: | pJA110 |
| GenBank Number: | K02043 |
| Species: | Homo sapiens, human |
| Applications: | Codominant segregation of the XhoI RFLP observed in 9 families. |
| Vector: | Construct size (kb): 4.300000190734863 |
| Insert: | DNA: genomic Insert lengths(kb): 1.0 Gene product: natriuretic peptide precursor A(pronatriodilatin) PND Alleles: A1, A2, A1, A2, B1, B2, C2, B1, B2, C1, C2, C1 |
| Insert Size (kb): | 1.0 |
| Related Products: | component of:ATCC 77175 |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
| Comments: | Restriction digests of the clone give the following sizes (kb): BamHI--4.3; EcoRI--4.3; XhoII--1.7, 1.2, 0.8, 0.4, 0.2; HindIII--uncut. Codominant segregation of the XhoI RFLP observed in 9 families. Includes about 500 bp upstream from site of initiation of transcription, exon 1, intron 1, and part of exon 2. Detection of the BglI polymorphism (alleles 10 and 6 kb) was verified by CEPH. Enzyme(s) not detecting polymorphism: EcoRI, BamHI, XbaI, ScaI, HindIII. |
| References: | Nemer M, et al. XhoI polymorphism at the human pronatriodilatin (hPND) gene locus. Nucleic Acids Res. 14: 8696, 1986. PubMed: 2878412 Bradley DG, et al. Autosomal dominant retinitis pigmentosa: exclusion of the gene from the short arm of chromosome 1 including the region surrounding the Rhesus locus. Am. J. Hum. Genet. 44: 570-576, 1989. PubMed: 2564733 Nemer M, et al. Gene structure of human cardiac hormone precursor, pronatriodilatin. Nature 312: 654-656, 1984. PubMed: 6095118 Yang-Feng TL, et al. The pronatriodilatin gene is located on the distal short arm of human chromosome 1 and on mouse chromosome 4. Am. J. Hum. Genet. 37: 1117-1128, 1985. PubMed: 2934979 Dracopoli NC, et al. The CEPH consortium linkage map of human chromosome 1. Genomics 9: 686-700, 1991. PubMed: 2037294 |