宁波泰斯拓生物

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浙江省宁波市镇海区庄市街道兴庄路9号创e慧谷42号楼B幢401室
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pCII-711

货号 TS161921
中文名称 null
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产品名称: pCII-711
商品货号: TS161921
Designations: pCII-711
GenBank Number:

K00946

Species: Homo sapiens, human
Vector:
Construct size (kb): 4.300000190734863
Insert:
DNA: cDNA
Insert lengths(kb): 0.5
Tissue: liver
Gene product: apolipoprotein C-II APOC2
Alleles: T1, T2
Insert Size (kb): 0.5
Biosafety Level: 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Shipping Information: Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug)
Comments:
Restriction digests of the clone give the following sizes (kb): PstI--3.8, 0.5; SalI--4.3; PvuII--4.3; BamHI--4.3; HindIII--4.3.
The insert includes the entire coding sequence (plus part of signal peptide), 144 bp of the 3 untranslated region, and poly(A) tail.
The insert corresponds to mRNA coding for entire plasma form of APOC2.
The polymorphic TaqI site is about 2 kb 3 of APOC2 gene; the site is in linkage disequilibrium with BanI site.
References:

Jackson CL, et al. Isolation and sequence of a human apolipoprotein CII cDNA clone and its use to isolate and map to human chromosome 19 the gene for apolipoprotein CII. Proc. Natl. Acad. Sci. USA 81: 2945-2949, 1984. PubMed: 6328478

Lusis AJ, et al. Regional mapping of human chromosome 19: organization of genes for plasma lipid transport (APOC1, -C2, and -E and LDLR) and the genes C3, PEPD, and GPI. Proc. Natl. Acad. Sci. USA 83: 3929-3933, 1986. PubMed: 3459164