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微信小章| 产品名称： | p47phox-pK Clone C, clone K, p47 |
|---|---|
| 商品货号： | TS163239 |
| Designations： | p47phox-pK Clone C, clone K, p47 |
| GenBank Number： | M26193 |
| Species： | Homo sapiens, human |
| Applications： | produces protein neutrophil cytosolic factor 1 (47kD, chronic granulomatous disease, autosomal 1) neutrophil cytosolic factor 1 |
| Vector： | Construct size (kb): 4.300000190734863 |
| Insert： | DNA: cDNA Insert lengths(kb): 1.350000023841858 Tissue: HL-60 cell line (DMSO induced) Gene product: neutrophil cytosolic factor 1 (47kD, chronic granulomatous disease, autosomal 1)(neutrophil cytosolic factor 1) NCF1 Target Gene: neutrophil cytosolic factor 1 (47kD, chronic granulomatous disease, autosomal 1) |
| Insert Size (kb)： | 1.350 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
| Comments： | Restriction digests of the clone give the following sizes (kb): BamHI--3.7, 0.64; EcoRI--3.0, 1.35; HindIII--4.4; PstI--3.3, 0.5, 0.27; XbaI--4.4. The insert contains the following restriction sites (nt from the 5 EcoRI site): XmnI--72, AccI--142, BglII--159, PstI--318; BamHI--634; NarI--916; SmaI--1060. This clone encodes the synthesis of a 50 kDa fusion protein recognized by anti-NADPH oxidase antisera. Detects a mRNA of 1.4 kb. |
| References： | Volpp BD, et al. Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase. Proc. Natl. Acad. Sci. USA 86: 7195-7199, 1989. PubMed: 2550933 Volpp BD, et al. Two cytosolic neutrophil oxidase components absent in autosomal chronic granulomatous disease. Science 242: 1295-1297, 1988. PubMed: 2848318 . Medical sciences: correction. Proc. Natl. Acad. Sci. USA 86: 9563, 1989. Casimir CM, et al. Autosomal recessive chronic granulomatous disease caused by deletion at a dinucleotide repeat. Proc. Natl. Acad. Sci. USA 88: 2753-2757, 1991. PubMed: 2011585 |