| 产品名称: | phpim5R1 hpim-1, pHPimR1 |
|---|---|
| 商品货号: | TS164675 |
| Designations: | phpim5R1 hpim-1, pHPimR1 |
| Species: | Homo sapiens, human |
| Vector: | Construct size (kb): 6.400000095367432 |
| Insert: | DNA: genomic Insert lengths(kb): 3.599999904632568 Tissue: 380 cell line Gene product: proviral integration, MCF PIM Alleles: A1, A2, B1, B2, C1, A1, A2, B1, B2, C1, C2, C2 |
| Insert Size (kb): | 3.600 |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
| Comments: | Restriction digests of the clone give the following sizes (kb): EcoRI--3.9, 3.05; HindIII--3.6, 2.5, 0.9; PstI--2.45, 1.5, 1.2, 1.1, 0.54; BamHI--5.2, 1.2, 0.48; SalI--7.0. Insert contains BamHI (2) and HindIII (2) sites. Includes part of intron 4, exon 5, intron 5, exon 6, and 3 flanking sequences. Cross-hybridizes to mouse Pim-1 gene under stringent conditions. Vector PyT is a pBR322 derivative with a deletion between EcoRII sites 1058 and 2500. Enzyme(s) not detecting polymorphism: EcoRI, HindIII. |
| References: | Zoghbi HY, et al. Deletion and linkage mapping of eight markers from the proximal short arm of chromosome 6. Genomics 6: 352-357, 1990. PubMed: 1968423 Nagarajan L, et al. Localization of the human pim oncogene (PIM) to a region of chromosome 6 involved in translocations in acute leukemias. Proc. Natl. Acad. Sci. USA 83: 2556-2560, 1986. PubMed: 3458216 Meeker TC, et al. Characterization of the human PIM-1 gene: a putative proto-oncogene coding for a tissue specific member of the protein kinase family. Oncogene Res. 1: 87-101, 1987. PubMed: 3329711 |