宁波泰斯拓生物

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浙江省宁波市镇海区庄市街道兴庄路9号创e慧谷42号楼B幢401室
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phins 310 [pHINS310]

货号 TS164963
中文名称 null
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产品名称: phins 310 pHINS310
商品货号: TS164963
Designations: phins 310 pHINS310
GenBank Number:

J00265

Species: Homo sapiens, human
Vector:
Construct size (kb): 4.199999809265137
Insert:
DNA: genomic
Insert lengths(kb): 0.8799999952316284
Gene product: insulin INS
Alleles: K2, A3, B2, A1, A1, A4, A3, A3, A5, A6, B1, K1, A1, A2, A2, A2
Insert Size (kb): 0.880
Biosafety Level: 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Comments:
Restriction digests of the clone give the following sizes (kb): BamHI--3.3, 0.88; EcoRI--4.2; HindIII--4.2, PstI--3.0, 1.2; PvuII--uncut.
Insert is the 5 flanking insulin gene-linked hypervariable region. Insert had BamHI linkers added.
References:

Radice P, et al. Loss of heterozygosity in human germinal tumors. Cytogenet. Cell Genet. 52: 72-76, 1989. PubMed: 2612217

Georges M, et al. On the use of DNA fingerprints for linkage studies in cattle. Genomics 6: 461-474, 1990. PubMed: 1970327

Misra BC, Srivatsan ES. Localization of HeLa cell tumor-suppressor gene to the long arm of chromosome II. Am. J. Hum. Genet. 45: 565-577, 1989. PubMed: 2577469

Egeland JA, et al. Bipolar affective disorders linked to DNA markers on chromosome 11. Nature 325: 783-787, 1987. PubMed: 2881209

Bell GI, et al. A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus. Diabetes 33: 176-183, 1984. PubMed: 6363172

. . Cytogenet. Cell Genet. 40: 406-407, 1985.

Detera-Wadleigh SD, et al. Close linkage of c-Harvey-ras-1 and the insulin gene to affective disorder is ruled out in three North American pedigrees. Nature 325: 806-808, 1987. PubMed: 3547139