| 产品名称: | phins 310 pHINS310 |
|---|---|
| 商品货号: | TS164963 |
| Designations: | phins 310 pHINS310 |
| GenBank Number: | J00265 |
| Species: | Homo sapiens, human |
| Vector: | Construct size (kb): 4.199999809265137 |
| Insert: | DNA: genomic Insert lengths(kb): 0.8799999952316284 Gene product: insulin INS Alleles: K2, A3, B2, A1, A1, A4, A3, A3, A5, A6, B1, K1, A1, A2, A2, A2 |
| Insert Size (kb): | 0.880 |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Comments: | Restriction digests of the clone give the following sizes (kb): BamHI--3.3, 0.88; EcoRI--4.2; HindIII--4.2, PstI--3.0, 1.2; PvuII--uncut. Insert is the 5 flanking insulin gene-linked hypervariable region. Insert had BamHI linkers added. |
| References: | Radice P, et al. Loss of heterozygosity in human germinal tumors. Cytogenet. Cell Genet. 52: 72-76, 1989. PubMed: 2612217 Georges M, et al. On the use of DNA fingerprints for linkage studies in cattle. Genomics 6: 461-474, 1990. PubMed: 1970327 Misra BC, Srivatsan ES. Localization of HeLa cell tumor-suppressor gene to the long arm of chromosome II. Am. J. Hum. Genet. 45: 565-577, 1989. PubMed: 2577469 Egeland JA, et al. Bipolar affective disorders linked to DNA markers on chromosome 11. Nature 325: 783-787, 1987. PubMed: 2881209 Bell GI, et al. A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus. Diabetes 33: 176-183, 1984. PubMed: 6363172 . . Cytogenet. Cell Genet. 40: 406-407, 1985. Detera-Wadleigh SD, et al. Close linkage of c-Harvey-ras-1 and the insulin gene to affective disorder is ruled out in three North American pedigrees. Nature 325: 806-808, 1987. PubMed: 3547139 |