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| 产品名称： | pMEL34 |
|---|---|
| 商品货号： | TS168069 |
| Designations： | pMEL34 |
| GenBank Number： | J03581 |
| Species： | Homo sapiens, human |
| Vector： | Construct size (kb): 4.900000095367432 |
| Insert： | DNA: cDNA Insert lengths(kb): 1.600000023841858 Tissue: melanocyte Gene product: tyrosinase c Alleles: c, c, s, s, B1, B2 |
| Insert Size (kb)： | 1.600 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
| Comments： | Restriction digests of the clone give the following sizes (kb): EcoRI--3.0, 1.85; XbaI--4.9; SmaI--4.9; ClaI--4.9; HindIII--4.9. Detects genomic EcoRI fragments of 4.5, 12.0, and 14.5 kb in c(ch)/c(ch) mice. No homologous sequences were detected in albino mutants c(14Cos)/c(14Cos) or c(3H)/c(3H). Detects a mRNA of 2.4 kb (21S) in normal human melanocytes and melanotic melanoma cells. |
| References： | Spritz RA, Strunk KM. RFLP for BglII at the human tyrosinase (TYR) locus. Nucleic Acids Res. 18: 3672, 1990. PubMed: 1972982 Kwon BS, et al. Isolation and sequence of a cDNA clone for human tyrosinase that maps at the mouse c-albino locus. Proc. Natl. Acad. Sci. USA 84: 7473-7477, 1987. PubMed: 2823263 |