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| 产品名称： | p4D8-IV |
|---|---|
| 商品货号： | TS168288 |
| Designations： | p4D8-IV |
| Species： | Homo sapiens, human |
| Vector： | Construct size (kb): 9.699999809265137 |
| Insert： | DNA: genomic Insert lengths(kb): 7.0 Tissue: lymphoblast GM1416 (48,XXXX) cell line Gene product: DNA Segment, single copy DXS98 Alleles: A1, B1, B2, C1, C2, D2, D1, A2 |
| Insert Size (kb)： | 7.0 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
| Comments： | Restriction digests of the clone give the following sizes (kb): EcoRI--5.7, 4.0; HindIII--8.3, 1.4; BamHI--7.0, 2.7; PstI--5.4, 4.3; SalI--9.7. This insert is repeat-free. The insert contains part of the original HindIII fragment of p4D-8 (ATCC 57060, 57061). A BamHI/XbaI fragment of this clone (p4D8-IVe) detects one of the two XmnI RFLPs (D1, D2) more clearly (1.5% agarose gels, 16 cm migration of 1.35 kb marker). DXS98 shows close linkage to FRAXA (theta = 0.10, LOD score = 17.31). DXS98 is proximal to FRAXA by in situ hybridization. Combined heterozygosity for the polymorphisms detected by p4D-8 (ATCC 57060, 57061), p4D8-B (ATCC 61572, 61573), and p4D8-IV (ATCC 61574, 61575) is 48%. |
| References： | Schnur RE, et al. New polymorphisms at the DXS98 locus and confirmation of its location proximal to FRAXA by in situ hybridization. Am. J. Hum. Genet. 44: 248-254, 1989. PubMed: 2563194 |