| 产品名称: | 45.1 DPbeta 003 |
|---|---|
| 商品货号: | TS170260 |
| Designations: | 45.1 DPbeta 003 |
| GenBank Number: | X03067 |
| Species: | Homo sapiens, human |
| Vector: | Construct size (kb): 3.700000047683716 |
| Insert: | DNA: cDNA Insert lengths(kb): 1.172000050544739 Tissue: hemizygous 45.1 cell line (DR1, DQw1, DPw2) Gene product: major histocompatibility complex, class II, DP beta 2 (pseudogene) HLA-DP2B |
| Insert Size (kb): | 1.172 |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
| Comments: | Restriction digests of the clone give the following sizes (kb): BamHI--2.6, 1.1; SalI--3.4, 0.4; PvuII--3.4; XbaI--3.5; SmaI--3.7; PstI--2.4, 1.1, 0.4. The open reading frame contains 257 codons, flanked by 51 bp of 5 untranslated region and 259 bp of 3 untranslated region. Encodes complete sequence of DPw2 chain. BamHI site at 3 end is within SV40 sequence (coordinates 0.715-0.710). Insert cut out with BamHI will include approx. 35 bp of SV40 sequence. |
| References: | Tonnelle C, et al. DObeta: a new beta chain gene in HLA-D with a distinct regulation of expression. EMBO J. 4: 2839-2847, 1985. PubMed: 2998758 Dixon MJ, et al. Association of Treacher Collins syndrome and translocation 6p21.31/16p13.11: exclusion of the locus from these candidate regions. Am. J. Hum. Genet. 48: 274-280, 1991. PubMed: 1671319 |