宁波泰斯拓生物

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45.1 DPbeta 003

货号 TS170260
中文名称 null
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产品简介
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产品名称: 45.1 DPbeta 003
商品货号: TS170260
Designations: 45.1 DPbeta 003
GenBank Number:

X03067

Species: Homo sapiens, human
Vector:
Construct size (kb): 3.700000047683716
Insert:
DNA: cDNA
Insert lengths(kb): 1.172000050544739
Tissue: hemizygous 45.1 cell line (DR1, DQw1, DPw2)
Gene product: major histocompatibility complex, class II, DP beta 2 (pseudogene) HLA-DP2B
Insert Size (kb): 1.172
Biosafety Level: 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Shipping Information: Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng)
Comments:
Restriction digests of the clone give the following sizes (kb): BamHI--2.6, 1.1; SalI--3.4, 0.4; PvuII--3.4; XbaI--3.5; SmaI--3.7; PstI--2.4, 1.1, 0.4.
The open reading frame contains 257 codons, flanked by 51 bp of 5 untranslated region and 259 bp of 3 untranslated region.
Encodes complete sequence of DPw2 chain. BamHI site at 3 end is within SV40 sequence (coordinates 0.715-0.710). Insert cut out with BamHI will include approx. 35 bp of SV40 sequence.
References:

Tonnelle C, et al. DObeta: a new beta chain gene in HLA-D with a distinct regulation of expression. EMBO J. 4: 2839-2847, 1985. PubMed: 2998758

Dixon MJ, et al. Association of Treacher Collins syndrome and translocation 6p21.31/16p13.11: exclusion of the locus from these candidate regions. Am. J. Hum. Genet. 48: 274-280, 1991. PubMed: 1671319