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微信小章| 产品名称： | pFH154 |
|---|---|
| 商品货号： | TS170408 |
| Designations： | pFH154 |
| GenBank Number： | X02761 |
| Species： | Homo sapiens, human |
| Depositors： | FE Baralle |
| Vector： | Construct size (kb): 6.5 |
| Insert： | DNA: cDNA Insert lengths(kb): 2.5 Tissue: Hs578T cell line Gene product: fibronectin 1 FN1 Alleles: A2, E2, A1, B2, D2, B1, D1, E1 |
| Insert Size (kb)： | 2.5 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
| Comments： | Restriction digests of the clone give the following sizes (kb): PvuII--5.3, 0.7; HindIII--6.1; BamHI--4.8, 1.4; HindIII/BamHI--3.4, 1.4 (doublet); EcoRI--4.8, 1.5. Waldenburg syndrome shows close linkage to FN1 and ALPP in one multigenerational family with 11 affected individuals. |
| References： | Kornblihtt AR, et al. Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene. EMBO J. 4: 1755-1759, 1985. PubMed: 2992939 Asher JH Jr., et al. Waardenburg syndrome (WS): the analysis of a single family with a WS1 mutation showing linkage to RFLP markers on human chromosome 2q. Am. J. Hum. Genet. 48: 43-52, 1991. PubMed: 1670751 Gardella R, et al. A common MspI RFLP of the human fibronectin gene (FN1). Nucleic Acids Res. 16: 1651, 1988. PubMed: 2450335 |