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| 产品名称： | pHexA49 |
|---|---|
| 商品货号： | TS170771 |
| Designations： | pHexA49 |
| GenBank Number： | M13520 |
| Species： | Homo sapiens, human |
| Vector： | Construct size (kb): 5.099999904632568 |
| Insert： | DNA: cDNA Insert lengths(kb): 2.099999904632568 Tissue: SV40-transformed fibroblast Gene product: hexosaminidase A (alpha polypeptide)( Hexose aminidase A (alpha polypeptide), beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase) HEXA Alleles: A2, A1, A1, A2 |
| Insert Size (kb)： | 2.100 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: DNA distributed as 5 ug in 50 ul TE (volume: 50 ul, |
| Comments： | Restriction digests of the clone give the following sizes (kb): XhoI--3.0, 1.9; HindIII--5.1; PstI--3.7, 1.3; EcoRI--uncut; BamHI--3.2, 1.9. Contains proximal one of 2 potential polyA sites for HEXA. Insert excised by XhoI will include some SV40 sequence. Enzyme(s) not detecting polymorphism: EcoRI, BglII, HincII, BamHI, HindIII, PstI. |
| References： | Neote K, et al. A rare insertion/deletion polymorphism at the HEXA locus. Nucleic Acids Res. 19: 683, 1991. PubMed: 1826352 Korneluk RG, et al. Isolation of cDNA clones coding for the alpha-subunit of human beta-hexosaminidase. Extensive homology between the alpha- and beta-subunits and studies on Tay-Sachs disease. J. Biol. Chem. 261: 8407-8413, 1986. PubMed: 3013851 |