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| 产品名称： | Y-280 |
|---|---|
| 商品货号： | TS172006 |
| Designations： | Y-280 |
| Species： | Homo sapiens, human |
| Vector： | Construct size (kb): 6.599999904632568 |
| Insert： | DNA: genomic Insert lengths(kb): 2.200000047683716 Tissue: 49,XXXXY cell line Gene product: DNA Segment, repetitive DYZ5 |
| Insert Size (kb)： | 2.200 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
| Comments： | Restriction digests of the clone give the following sizes (kb): EcoRI--7.0; HindIII--4.6, 2.4; EcoRI/BamHI--4.4, 2.9; BamHI--7.0; AvaI--7.0; PvuII--7.0. This probe detects sequences in the distal end of Yp. In HindIII digests, hybridizes to a 2.2 kb Y-specific fragment and 2 larger autosomal polymorphic fragments. Y-specificity was found in 9 of 11 XX males. No Y-specific hybridization detected in two 46,XX hermaphrodites. Isolated from a flow-sorted human Y chromosome library enriched for DNA from the Y euchromatic portion. |
| References： | Muller U, et al. Deletion mapping of the testis determining locus with DNA probes in 46,XX males and in 46,XY and 46,X,dic(Y) females. Nucleic Acids Res. 14: 6489-6505, 1986. PubMed: 3748818 Gaunt SJ. Mapping of testis-determining locus on Yp by the molecular genetic analysis of XX males and XY females. Development 101: 51-58, 1987. PubMed: 88211484 |