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| 产品名称： | p1516-R4 |
|---|---|
| 商品货号： | TS172585 |
| Designations： | p1516-R4 |
| Species： | Homo sapiens, human |
| Applications： | Codominant segregation of the MspI RFLP has been observed in 2 French-Acadian kindreds (58 individuals). |
| Vector： | Construct size (kb): 7.800000190734863 |
| Insert： | DNA: genomic Insert lengths(kb): 4.900000095367432 Gene product: DNA Segment, single copy D17S258 Alleles: A1, A2 |
| Insert Size (kb)： | 4.900 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
| Comments： | Restriction digests of the clone give the following sizes (kb): BamHI--4.9, 2.8; EcoRI--4.8, 3.0; HindIII--7.6; KpnI--5.6, 2.4; PstI--3.6, 1.6, 1.0, 0.9, 0.5, 0.4. Closely linked to Charcot-Marie-Tooth Disease Type 1A. Preassociation with human placental DNA is required prior to hybridization at normal stringency (65C, 1 M Na+). Codominant segregation of the MspI RFLP has been observed in 2 French-Acadian kindreds (58 individuals). Enzyme(s) not detecting polymorphism: RsaI, PvuII, PstI, TaqI, BglII, EcoRI (in a panel of 8 individuals). |
| References： | Franco B, et al. Two MspI RFLPs at the D17S258 locus. Nucleic Acids Res. 18: 7196, 1990. PubMed: 1702207 Patel PI, et al. Genetic mapping of autosomal dominant Charcot-Marie-Tooth disease in a large French-Acadian kindred: identification of new linked markers on chromosome 17. Am. J. Hum. Genet. 46: 801-809, 1990. PubMed: 2316525 |