宁波泰斯拓生物

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浙江省宁波市镇海区庄市街道兴庄路9号创e慧谷42号楼B幢401室
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pOR3

货号 TS172723
中文名称 null
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产品简介
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产品名称: pOR3
商品货号: TS172723
Designations: pOR3
GenBank Number:

M11457

Species: Homo sapiens, human
Depositors: P Chambon
Vector:
Construct size (kb): 5.599999904632568
Insert:
DNA: cDNA
Insert lengths(kb): 1.299999952316284
Tissue: breast adenocarcinoma MCF7 cell line
Gene product: estrogen receptor ESR
Alleles: s, b, A1, A2
Insert Size (kb): 1.300
Media: ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin
Biosafety Level: 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Shipping Information: Distributed: freeze-dried
Comments:
Restriction digests of the clone give the following sizes (kb): EcoRI--4.4, 1.35; BamHI--5.8; PstI--3.8, 1.04, 0.98; HindIII--5.3, 0.4; AvaI--3.0, 2.6.
Extends approximately from nt 300 - 1600 of the published sequence.
Contains sequences encoding the epitope recognized by MAb H226, believed to recognize the DNA-binding domain. This DNA-binding domain is in a 900 bp EcoRI/HindIII fragment and a 380 bp BalI fragment.
Includes sequences homologous to v-erb-A (aa 185-251).
References:

Justice MJ, et al. A genetic linkage map of mouse chromosome 10: localization of eighteen molecular markers using a single interspecific backcross. Genetics 125: 855-866, 1990. PubMed: 1975791

Castagnoli A, et al. PvuII RFLP inside the human estrogen receptor gene. Nucleic Acids Res. 15: 866, 1987. PubMed: 2881267

Walter P, et al. Cloning of the human estrogen receptor cDNA. Proc. Natl. Acad. Sci. USA 82: 7889-7893, 1985. PubMed: 3865204

Green S, et al. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature 320: 134-139, 1986. PubMed: 3754034

Kumar V, et al. Functional domains of the human estrogen receptor. Cell 51: 941-951, 1987. PubMed: 3690665