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微信小章| 产品名称： | phAT6.5 |
|---|---|
| 商品货号： | TS176503 |
| Designations： | phAT6.5 |
| GenBank Number： | M02212 |
| Species： | Homo sapiens, human |
| Depositors： | SL Woo |
| Vector： | Construct size (kb): 10.89999961853027 |
| Insert： | DNA: genomic Insert lengths(kb): 6.5 Tissue: liver Gene product: alpha-1-antitrypsin-like PI Alleles: G3, A1, A2, B1, B2, D2, G1, G2, J2, N1, N2, C1, C2, D1, J1, A1, A2, D1, D2 |
| Insert Size (kb)： | 6.5 |
| Media： | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: freeze-dried |
| Comments： | Restriction digests of the clone give the following sizes (kb): EcoRI--10.9; HindIII--6.6, 2.7, 0.5; PvuII--4.6, 1.7, 1.7; BamHI--6.4, 4.4; AvaI--4.0, 2.8, 2.5, 0.9. This BamHI fragment starts close to the 5 end of exon 2 and continues through to 3 flanking sequences. |
| References： | Long GL, et al. Complete sequence of the cDNA for human alpha1-antitrypsin and the gene for the S variant. Biochemistry 23: 4828-4837, 1984. PubMed: 6093867 Sifers RN, et al. A frameshift mutation results in a truncated alpha1-antitrypsin that is retained within the rough endoplasmic reticulum. J. Biol. Chem. 263: 7330-7335, 1988. PubMed: 3259232 Cox DW, et al. DNA restriction fragments associated with alpha1-antitrypsin indicate a single origin for deficiency allele PI Z. Nature 316: 79-81, 1985. PubMed: 2989709 |