| 产品名称: | pRXb1.8 probe A |
|---|---|
| 商品货号: | TS177883 |
| Designations: | pRXb1.8 probe A |
| Species: | Homo sapiens, human |
| Vector: | Construct size (kb): 4.5 |
| Insert: | DNA: genomic Insert lengths(kb): 1.799999952316284 Gene product: immunoglobulin heavy chain gamma IGHG@* |
| Insert Size (kb): | 1.800 |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
| Comments: | Restriction digests of the clone give the following sizes (kb): XbaI/HindIII--4.6; EcoRI--4.6; HindIII--4.6; EcoRI/XbaI--2.8, 1.8; EcoRI/HindIII--2.8, 1.8. This probe cross-hybridizes with highly homologous regions present 3 to the IGHG (G3, G1, GP, G2 and G4) genes. This is a 1.8 kb EcoRI/XbaI fragment ("probe A") located 11.2 kb 3 to IGHG4 and 11.8 kb 5 to IGHE, cloned into pUC19. |
| References: | Keyeux G, et al. A multigene deletion in the human IGH constant region locus involves highly homologous hot spots of recombination. Genomics 5: 431-441, 1989. PubMed: 2613231 |