微信小陈
微信小章| 产品名称： | Cryptococcus neoformans (Sanfelice) Vuillemin |
|---|---|
| 商品货号： | TS178227 |
| Deposited As： | Cryptococcus neoformans (Sanfelice) Vuillemin, anamorph |
| Strain Designations： | 309 (cap 67) |
| Alternate State： | Filobasidiella neoformans Kwon-Chung |
| Application： | Biomedical Research and Development Material Emerging infectious disease research |
| Biosafety Level： | 2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | freeze-dried |
| Type Strain： | no |
| Preceptrol®： | no |
| Comments： | Restored virulence and encapulation by complementation with a single gene mechanism of human T-lymphocyte activation expression of cytotoxic T lymphocyte antigen (CTLA-4) by T cells |
| Medium： | ATCC® Medium 28: Emmons modification of Sabourauds agar |
| Growth Conditions： | Temperature: 26.0°C |
| Sequenced Data： | Not available.
|
| Name of Depositor： | ES Jacobson |
| Isolation： | derived from existing strain |
| References： | Fromtling RA, et al. Decreased virulence in stable, acapsular mutants of cryptococcus neoformans. Mycopathologia 79: 23-29, 1982. PubMed: 6750405 Jacobson ES, Payne WR. UDP glucuronate decarboxylase and synthesis of capsular polysaccharide in Cryptococcus neoformans. J. Bacteriol. 152: 932-934, 1982. PubMed: 6752126 Still CN, Jacobson ES. Recombinational mapping of capsule mutations in Cryptococcus neoformans. J. Bacteriol. 156: 460-462, 1983. PubMed: 6352689 Jacobson ES, et al. Genetic and phenotypic characterization of capsule mutants of Cryptococcus neoformans. J. Bacteriol. 150: 1292-1296, 1982. PubMed: 7042689 Nosanchuk JD, et al. Amphotericin B and fluconazole affect cellular charge, macrophage phagocytosis, and cellular morphology of Cryptococcus neoformans at subinhibitory concentrations. Antimicrob. Agents Chemother. 43: 233-239, 1999. PubMed: 9925511 Mody CH, et al. The cell wall and membrane of Cryptococcus neoformans possess a mitogen for human T lymphocytes. Infect. Immun. 67: 936-941, 1999. PubMed: 9916111 Pietrella D, et al. Cytotoxic T lymphocyte antigen costimulation influences T-cell activation in response to Cryptococcus neoformans. Infect. Immun. 69: 1508-1514, 2001. PubMed: 11179320 acapsular mutant of NIH B-3501 |