| 产品名称: | 218EP6 218 |
|---|---|
| 商品货号: | TS178631 |
| Designations: | 218EP6 218 |
| Species: | Homo sapiens, human |
| Vector: | Construct size (kb): 6.099999904632568 |
| Insert: | DNA: genomic Insert lengths(kb): 1.700000047683716 Gene product: DNA Segment, single copy D16S246 Alleles: G1, G2, H1, A1, A2, B1, B2, C1, C2, D1, D2, E1, E2, F1, F2, H2 |
| Insert Size (kb): | 1.700 |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
| Comments: | Restriction digests of the clone give the following sizes (kb): PstI--4.37, 1.8, 0.5; HindIII--6.8; EcoRI--6.8; BamHI--6.8; HindIII/EcoRI--4.37, 2.3. This probe is localized proximal to CMM65 (D16S84) and distal to the breakpoint in GM2324 t(16;22) (p13.3;q21). Minor variations were detected in the allele fragment sizes, indicating this probe may be located close to a VNTR. Contains two PstI fragments subcloned from cosmid 218. The 1.7 kb fragment detects the RFLP. Also contains some mouse DNA. Enzyme(s) not detecting polymorphism: HindIII, SacI. |
| References: | Snijdewint FG, et al. Probe 218EP6 (D16S246) detects RFLPs close to the locus affecting adult polycystic kidney disease (PKD1) on chromosome 16. Nucleic Acids Res. 18: 3108, 1990. PubMed: 1971935 |