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| 产品名称： | Leptodontidium elatius (Mangenot) de Hoog var. elatius, anamorph |
|---|---|
| 商品货号： | TS181262 |
| Strain Designations： | MF5465 CIBE 8943-106F, Mycosearch 3137 |
| Application： | produces squalene synthetase inhibitor produces zaragozic acid C produces zaragozic acid E produces zaragozic acid F produces zaragozic acid C, a squalene synthetase inhibitor |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | freeze-dried |
| Type Strain： | no |
| Disclosure： | This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC. |
| Preceptrol®： | no |
| Medium： | ATCC® Medium 336: Potato dextrose agar (PDA) |
| Growth Conditions： | Temperature: 24.0°C |
| Name of Depositor： | Merck & Co., Inc. |
| U.S. Patent Number： | |
| Isolation： | dead wood, Joyce Kilmer Memorial Forest, Graham Co., NC |
| References： | Bartizal KF, Onishi JC. Method of inhibiting fungal growth using squalene synthetase inhibitors. US Patent 5,026,554 dated Jun 25 1991 Bergstrom JD, et al. Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase. Proc. Natl. Acad. Sci. USA 90: 80-84, 1993. PubMed: 8419946 Bills GF, et al. Distribution of zaragozic acids (squalestins) among filamentous ascomycetes. Mycol. Res. 98: 733-739, 1994. |