| 产品名称: | p9A7 |
|---|---|
| 商品货号: | TS181341 |
| Designations: | p9A7 |
| Species: | Homo sapiens, human |
| Depositors: | WK Cavenee |
| Vector: | Construct size (kb): 5.5 |
| Insert: | DNA: genomic Insert lengths(kb): 1.0 Gene product: DNA Segment, single copy D13S3 Alleles: A2, A3, B1, A1, B2 |
| Insert Size (kb): | 1.0 |
| Media: | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: freeze-dried |
| Comments: | Restriction digests of the clone give the following sizes (kb): HindIII--4.4, 1.2; BamHI--5.5; AccI--1.65, 2.0 (doublet). DNA marker in region of deletion of chromosome 13 to which gene predisposing to retinoblastoma has been mapped. |
| References: | Cavenee W, et al. Isolation and regional localization of DNA segments revealing polymorphic loci from human chromosome 13. Am. J. Hum. Genet. 36: 10-24, 1984. PubMed: 6320640 Dryja TP, et al. Chromosome 13 homozygosity in osteosarcoma without retinoblastoma. Am. J. Hum. Genet. 38: 59-66, 1986. PubMed: 3004203 Radice P, et al. Loss of heterozygosity in human germinal tumors. Cytogenet. Cell Genet. 52: 72-76, 1989. PubMed: 2612217 Chidambaram A, et al. A new, low frequency MspI allele at the D13S3 locus. Nucleic Acids Res. 18: 1317, 1990. PubMed: 1690877 Lundberg C, et al. Loss of heterozygosity in human ductal breast tumors indicates a recessive mutation on chromosome 13. Proc. Natl. Acad. Sci. USA 84: 2372-2376, 1987. PubMed: 3031679 Leppert M, et al. A primary genetic map of chromosome 13q. Am. J. Hum. Genet. 39: 425-437, 1986. PubMed: 3464200 |