| 产品名称: | int-2h |
|---|---|
| 商品货号: | TS183011 |
| Designations: | int-2h |
| Species: | Mus musculus, mouse |
| Depositors: | C Dickson, G Peters |
| Vector: | Construct size (kb): 4.5 |
| Insert: | DNA: genomic Insert lengths(kb): 1.5 Gene product: fibroblast growth factor-3( V-INT2 murine mammary tumor virus integration site oncogene homolog, murine mammary tumor virus integration site (v-int-2) oncogene homolog, murine mammary tumor virus integration site 2, mouse, included) Int2 Alleles: a, b |
| Insert Size (kb): | 1.5 |
| Media: | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: freeze-dried |
| Comments: | The insert contains KpnI, XbaI, and BglII sites. Restriction digests of the clone give the following sizes (kb): EcoRI/SacI--3.0, 1.5; BamHI--4.5; PstI--4.5; XbaI--4.3, 0.2; KpnI--4.5. The insert includes the integration site for mouse mammary tumor virus (MMTV) in the U163 (BT16) tumor. This insert maps 3 to the Int-2 coding sequences. |
| Classification: | Eukaryota, Animalia, Metazoa, Chordata, Vertebrata, Tetrapod |
| References: | Dixon M, et al. Detection and characterization of the fibroblast growth factor-related oncoprotein INT-2. Mol. Cell. Biol. 9: 4896-4902, 1989. PubMed: 2557543 Peters G, et al. Mouse mammary tumor virus integration regions int-1 and int-2 map on different mouse chromosomes. Mol. Cell. Biol. 4: 375-378, 1984. PubMed: 6321961 Dickson C, et al. Tumorigenesis by mouse mammary tumor virus: proviral activation of a cellular gene in the common integration region int-2. Cell 37: 529-536, 1984. PubMed: 6327073 Moore R, et al. Sequence, topography, and protein coding potential of mouse int-2: a putative oncogene activated by mouse mammry tumor virus. EMBO J. 5: 919-924, 1986. PubMed: 3013624 Clive Dickson, personal communication |