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| 产品名称： | p9-12A/2dIII2.5 p9-12A |
|---|---|
| 商品货号： | TS187589 |
| Designations： | p9-12A/2dIII2.5 p9-12A |
| Species： | Homo sapiens, human |
| Depositors： | BN White |
| Vector： | Construct size (kb): 5.0 |
| Insert： | DNA: genomic Insert lengths(kb): 2.5 Gene product: DNA Segment, single copy D10S5 Alleles: B2, B1, A2, C1, C2, A1 |
| Insert Size (kb)： | 2.5 |
| Media： | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: freeze-dried |
| Comments： | Restriction digests of the clone give the following sizes (kb): HindIII--2.6, 2.4; EcoRI/HindIII--2.6, 2.4; BamHI--5.0; SalI--5.0; PstI--5.0. A co-dominant segregation pattern in 5 families in which Multiple Endocrine Neoplasia Type 2A is present. Linkage between D10S5 and disease locus detected with a maximum LOD score of 3.58 at a recombination frequency of 0.19. Enzyme(s) not detecting polymorphism: MspI, HindIII. |
| References： | White RL, et al. The CEPH consortium primary linkage map of human chromosome 10. Genomics 6: 393-412, 1990. PubMed: 1970325 Simpson NE, et al. Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage. Nature 328: 528-530, 1987. PubMed: 2886918 McDermid HE, et al. A polymorphic locus, D10S5, at 10q21.1. Nucleic Acids Res. 15: 5498, 1987. PubMed: 2885808 |