| 产品名称: | phMnSOD4 |
|---|---|
| 商品货号: | TS193433 |
| Designations: | phMnSOD4 |
| GenBank Number: | Y00985 |
| Species: | Homo sapiens, human |
| Depositors: | GI Bell |
| Vector: | Construct size (kb): 3.900000095367432 |
| Insert: | DNA: cDNA Insert lengths(kb): 0.7799999713897705 Gene product: superoxide dismutase 2, mitochondrial SOD2 Alleles: A2, A1, B1, B2 |
| Insert Size (kb): | 0.780 |
| Media: | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: freeze-dried |
| Comments: | Restriction digests of the clone give the following sizes (kb): EcoRI--3.0, 0.73; PstI--3.7; BamHI--3.2, 0.55; PvuI--2.6, 1.2; AvaI--3.75. The insert encodes the complete 222 amino acid MnSOD precursor and contains 91 bp of 5 untranslated and 21 bp of 3 untranslated sequence, and poly(A). There are 2 TaqI polymorphisms which exhibit some linkage disequilibrium; the pairwise linkage disequilibrium value is 0.6 for Caucasians. Enzyme(s) not detecting polymorphism: BamHI, BglII, KpnI, RsaI. The insert contains the following restriction sites (approximate kb from the 5 end): PvuII--0.13, 0.24; BamHI--0.6. |
| References: | Sugaya K, et al. Molecular indices of neuronal and glial plasticity in the hippocampal formation in a rodent model of age-induced spatial learning impairment. J. Neurosci. 16: 3427-3443, 1996. PubMed: 8627377 Xiang K, et al. Multiple TaqI RFLPs at the human manganese superoxide dismutase (SOD2) locus on chromosome 6. Nucleic Acids Res. 15: 7654, 1987. PubMed: 2889193 |