| 产品名称: | p7F12 |
|---|---|
| 商品货号: | TS197316 |
| Designations: | p7F12 |
| Species: | Homo sapiens, human |
| Depositors: | WK Cavenee |
| Vector: | Construct size (kb): 8.600000381469727 |
| Insert: | DNA: genomic Insert lengths(kb): 4.199999809265137 Gene product: DNA Segment, single copy D13S1 Alleles: B1, B2, A1, A2 |
| Insert Size (kb): | 4.200 |
| Media: | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: freeze-dried |
| Comments: | Restriction digests of the clone give the following sizes (kb): HindIII--4.3, 4.2; BamHI--8.6; AccI--4.0, 2.9, 1.6. D13S1 is linked to Wilson disease (WD) on 13q (LOD score = 2.189, theta = 0.06) in populations of mixed European backgrounds and Hispanic. |
| References: | Cavenee W, et al. Isolation and regional localization of DNA segments revealing polymorphic loci from human chromosome 13. Am. J. Hum. Genet. 36: 10-24, 1984. PubMed: 6320640 Dryja TP, et al. Chromosome 13 homozygosity in osteosarcoma without retinoblastoma. Am. J. Hum. Genet. 38: 59-66, 1986. PubMed: 3004203 Radice P, et al. Loss of heterozygosity in human germinal tumors. Cytogenet. Cell Genet. 52: 72-76, 1989. PubMed: 2612217 Lundberg C, et al. Loss of heterozygosity in human ductal breast tumors indicates a recessive mutation on chromosome 13. Proc. Natl. Acad. Sci. USA 84: 2372-2376, 1987. PubMed: 3031679 Leppert M, et al. A primary genetic map of chromosome 13q. Am. J. Hum. Genet. 39: 425-437, 1986. PubMed: 3464200 Yuzbasiyan-Gurkan V, et al. Linkage of the Wilson disease gene to chromosome 13 in North-American pedigrees. Am. J. Hum. Genet. 42: 825-829, 1988. PubMed: 3163469 |