| 产品名称: | pHexB43 pHex1 |
|---|---|
| 商品货号: | TS202627 |
| Designations: | pHexB43 pHex1 |
| Species: | Homo sapiens, human |
| Depositors: | RA Gravel, DL Mahuran |
| Vector: | Construct size (kb): 5.199999809265137 |
| Insert: | DNA: cDNA Insert lengths(kb): 1.799999952316284 Tissue: SV40-transformed fibroblast Gene product: hexosaminidase B (beta polypeptide)(N-acetyl-beta-glucosaminidase) HEXB Alleles: E2, D1, D2, E1 |
| Insert Size (kb): | 1.800 |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
| Comments: | Restriction digests of the clone give the following sizes (kb): XhoI--3.1, 2.1; HindIII--3.2, 1.9 + smaller; PstI--2.2, 1.75, 1.4; EcoRI--4.9, 0.5; BamHI--3.2, 1.45, 0.7. Insert excised from plasmid by XhoI will include some SV40 sequences. |
| References: | ODowd BF, et al. Isolation of cDNA clones coding for the beta subunit of human beta-hexosaminidase. Proc. Natl. Acad. Sci. USA 82: 1184-1188, 1985. PubMed: 2579389 Weiffenbach B, et al. A genetic linkage map of human chromosome 5 with 60 RFLP loci. Genomics 10: 173-185, 1991. PubMed: 1675192 Korneluk RG, et al. Isolation of cDNA clones coding for the alpha-subunit of human beta-hexosaminidase. Extensive homology between the alpha- and beta-subunits and studies on Tay-Sachs disease. J. Biol. Chem. 261: 8407-8413, 1986. PubMed: 3013851 |