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微信小章| 产品名称： | int-2b |
|---|---|
| 商品货号： | TS205456 |
| Designations： | int-2b |
| GenBank Number： | Y00848 |
| Species： | Mus musculus, mouse |
| Depositors： | C Dickson, G Peters |
| Vector： | Construct size (kb): 5.099999904632568 |
| Insert： | DNA: genomic Insert lengths(kb): 2.099999904632568 Gene product: fibroblast growth factor-3( V-INT2 murine mammary tumor virus integration site oncogene homolog, murine mammary tumor virus integration site (v-int-2) oncogene homolog, murine mammary tumor virus integration site 2, mouse, included) Int2 Alleles: a, b |
| Insert Size (kb)： | 2.100 |
| Media： | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: freeze-dried |
| Comments： | The insert contains a BamHI, a BglII, and a PstI site. Restriction digests of the clone give the following sizes (kb): SacI--3.0, 2.4; EcoRI/PstI--2.8, 1.9, 0.3, 0.2; BamHI--5.4; XbaI--5.4; HindIII--5.4. The insert includes sequences at which the U5E, U98 (BT13B), CT4, T108 (BT11), U5A, X69B, U5F, X69A and B1 tumors show integration of mouse mammary tumor virus (MMTV). This insert maps 5 to the Int-2 coding sequences. The sequence of the 3 BamHI-SacI fragment (413 nucleotides) has been reported. |
| Classification： | Eukaryota, Animalia, Metazoa, Chordata, Vertebrata, Tetrapod |
| References： | Dixon M, et al. Detection and characterization of the fibroblast growth factor-related oncoprotein INT-2. Mol. Cell. Biol. 9: 4896-4902, 1989. PubMed: 2557543 Peters G, et al. Mouse mammary tumor virus integration regions int-1 and int-2 map on different mouse chromosomes. Mol. Cell. Biol. 4: 375-378, 1984. PubMed: 6321961 Dickson C, et al. Tumorigenesis by mouse mammary tumor virus: proviral activation of a cellular gene in the common integration region int-2. Cell 37: 529-536, 1984. PubMed: 6327073 Moore R, et al. Sequence, topography, and protein coding potential of mouse int-2: a putative oncogene activated by mouse mammry tumor virus. EMBO J. 5: 919-924, 1986. PubMed: 3013624 Clive Dickson, personal communication |