Hydrolyzes 1,2-dihydronaphthalene

Hydrolyzes 1,2-epoxyindene

Hydrolyzes styrene oxide

Hydroxylates polycyclic enones

Metabolizes phencyclidine

Oxidizes arteether

Oxidizes dialkylbenzen Hydroxylates e

Produces 2-deuterio-cycloalkanones

Produces 3-deuterio-cycloalkanones

Produces carbomycin derivatives magnamycin derivatives

Produces hydroxymethylpyridines (isomeric)

Produces leucomycin derivatives

Produces niddamycin derivatives

Hydroxylation of 7-azabrendane and 6-azatwistane derivatives

Hydroxylation of synthetic polycyclic enones

Reduction of alpha, beta-unsaturated ketones

Converts isosorbide dinitrate to isosorbide 5-mononitrate

Transformation of pergolide to pergolide sulfoxide

Glycosylation of 2,2,5,7,8-pentamethyl-6-hydroxychroman

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Temperature: 24°C to 26°C

Atmosphere: Typical aerobic

18S ribosomal RNA gene, partial sequence; internal   transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence

GGTCTCCGTTGGTGAACCAGCGGAGGGATCATTACCGAGTTTTCAACTCCCTAACCCTTCTGTGAACCTACCTATCGTTGCTTCGGCGGACTCGCCCCAGCCCGGACGCGGACTGGACCAGCGGCCCGCCGGGGACCTCAAACTCTTGTATTCCAGCATCTTCTGAATACGCCGCAAGGCAAAACAAATGAATCAAAACTTTCAACAACGGATCTCTTGGCTCTGGCATCGATGAAGAACGCAGCGAAACGCGATAAGTAATGTGAATTGCAGAATCCAGTGAATCATCGAATCTTTGAACGCACATTGCGCCCGCCAGCATTCTGGCGGGCATGCCTGTTCGAGCGTCATTTCAACCCTCGACCTCCCCTTGGGGAGGTCGGCGTTGGGGACCGGCAGCACACCGCCGGCCCTGAAATGGAGTGGCGGCCCGTCCGCGGCGACCTCTGCGCAGTAATACAGCTCGCACCGGAACCCCGACGCGGCCACGCCGTAAAACACCCAACTTCTGAACGTTGACCTCGAATCAGGTAGGACTACCCGCTGAACTTAAGCATATCAATAA

D1D2 region of the 28S ribosomal RNA gene

ATATCAATAAGCGGAGGAAAAGAAACCAACAGGGATTGCCCCAGTAACGGCGAGTGAAGCGGCAACAGCTCAAATTTGAAATCTGGCTCTCAGGGCCCGAGTTGTAATTTGTAGAGGATGCTTTTGGCGAGGTGCCTTCCGAGTTCCCTGGAACGGGACGCCACAGAGGGTGAGAGCCCCGTATGGTCGGACACCGAGCCTCTGTAAAGCTCCTTCGACGAGTCGAGTAGTTTGGGAATGCTGCTCAAAATGGGAGGTATATGTCTTCTAAAGCTAAATATTGGCCAGAGACCGATAGCGCACAAGTAGAGTGATCGAAAGATGAAAAGCACTTTGAAAAGAGGGTTAAAAAGTACGTGAAATTGTTGAAAGGGAAGCGCCTATGACCAGACTTGCGCCCGGTGAATCACCCAGCGTTCTCGCTGGTGCACTTTGCCGGGCACAGGCCAGCATCAGTTCAGCGCGGGGGAGAAAGGCTTCGGGAATGTGGCTCCCTCGGGAGTGTTATAGCCCGCTGCGTAATGCCCTGCGCCGGACTGAGGTACGCGCATTGCAAGGATGCTGGCGTAATGGTCATCAGCGAC

RNA polymerase II largest subunit gene (RPB1)

CCATATAGAGCTGGCGAAACCTGTCTATCACCCTGGTTTCATCAAGAAAGTGAAAAAGGTTTTGGAGATTGTCTGCCACAACTGCAGCAAAGTGTTGGCCGATGAAGTTGGTCTTCCCTTTACTCCATGAAGCTCTGGAGCTTGCTGGATGCTAACGTGCATTATCAGAGCGATCCCGAATTCGTCACAGCTATTCATACTCGCGATCCGAAACTCCGATTCAAGCGCGTTTGGGCCGTATGCAAGAAGAAGCGCAAATGCGAGAATGAGGAGCGGCAAGACAAGAATAAAGACGAAGAGTTCGCTCCAGGTGTCAAGAACGTCGTTCTCGAAGGACATGGCGGATGTGGCAATATGCAGCCGCAGGTGAGACAGGCCGCGCTGCAACTCAAAGCTGCCTTCGAGGTTACTTCGGAAGAGGGTCCCAAGAGGAAAGAGACGGTTAATATCAGCGCCGAGATGGCGCATGGTATCCTTCGCCGCATCTCTGAGCGCGATCTGCACAATATTGGTCTTAACTCAGACTATGCTCGTCCCGAGTGGATGATCATCACTGTCCTGCCTGTACCCCCTCCTCCCGTGCGTCCTAGTATTTCCATGGATGGTACTGGTACTGGCACGAGAAACGAGGATGATCTGACCTACAAGCTTGGTGACATTATCCGCGCCAACGGAAATGTCAAGCAGGCCATTCGTGAAGGATCACCGCAACACATCGCGCGTGATTTTGAGGAGCTGCTGCAGTACCATGTTGCCACC

ATCC <-- CBS <-- F.H. van Beyma

Laboratory contaminant

Ropenga JS, et al. Isosorbide dinitrate bioconversion by Beauveria strains: implication of glutathione transferase levels. Appl. Microbiol. Biotechnol. 31: 176-178, 1989.

Pedragosa-Moreau S, et al. Microbiological transformations. 28. Enantiocomplementary epoxide hydrolyses as a preparative access to both enantiomers of styrene oxide. J. Org. Chem. 58: 5533-5536, 1993.

Theriault RJ. Mycarosyl macrolide antibiotics. US Patent 3,784,447 dated Jan  8 1974

Taylor JJ. Further clarification of Sporotrichum species.  Mycologia 62: 823, 1970.

Johnson RA, et al. Microbial oxygenation of dialkylbenzenes. Bioorg Chem 2: 99-110, 1973.

Kergomard A, et al. Microbiological reduction of alpha,beta-unsaturated ketones by Beauveria sulfurescens.  J. Org. Chem. 47: 792-798, 1982.

Hu Y, et al. Microbial oxidataion of the antimalarial drug arteether.  Bioorg. Chem. 20: 148-154, 1992.

Hufford CD, et al. Metabolism of phencyclidine by microorganisms.  J. Pharm. Sci. 70: 155-158, 1981. PubMed: 7205218

Furstoss R, et al. Microbiological transformations 2. Hydroxylations of non activated carbons in globular type amides. Tetrahedron Lett 22: 445-448, 1981.

Dauphin G, et al. Microbiological synthesis and circular dichroism of optically active 2-deuterio-cycloalkanones. Tetrahedron Lett 21: 4275-4278, 1980.

Pedragosa-Moreau S, et al. Microbiological transformations. 31: Synthesis of enantiopure epoxides and vicinal diols using fungal epoxide hydrolase mediated hydrolysis.  Tetrahedron Lett. 37: 3319-3322, 1996.

Dauphin G, et al. Microbial glycosylation of 2, 2, 5, 7, 8-pentamethyl- 6-hydroxychroman. Agric Biol Chem 53: 1433-1435, 1989.

Dauphin G, et al. Microbiological synthesis of optically active 3-deuterio-cycloalkanones. J. Chem. Soc. Chem. Commun. 1980: 318-319, 1980.

Smith RV, et al. Microbial transformations of pergolide to pergolide sulfoxide and pergolide sulfone.  J. Pharm. Sci. 72: 733-736, 1983. PubMed: 6684155

Modyanova LV, et al. Microbial transformation of nitrogen-containing heterocyclic compounds. I. Hydroxylation of isomeric monomethylpyridines and dimethylpyridines by microscopic fungi. Biotekhnologiya 3: 24-27, 1990.

Hammoumi A, et al. Microbial hydroxylation and functionalization of synthetic polycyclic enones. Tetrahedron Asymmetry 4: 1295-1306, 1993.

Xu Y, et al. Biosynthesis of the cyclooligomer depsipeptide bassianolide, an insecticidal virulence factor of Beauveria bassiana. Fungal Genet. Biol. 46: 353-364, 2009. PubMed: 19285149

Xu Y, et al. Biosynthesis of the cyclooligomer depsipeptide beauvericin, a virulence factor of the entomopathogenic fungus Beauveria bassiana. Chem. Biol. 15: 898-907, 2008. PubMed: 18804027

type strain of Sporotrichum sulfurescens