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微信小章| 产品名称： | Cunninghamella elegans Lendner |
|---|---|
| 商品货号： | TS205777 |
| Deposited As： | Cunninghamella blakesleeana Lendner |
| Strain Designations： | NRRL 1369 DSM 1906, IMI 53585, IMI 63877 |
| Application： | oxidizes ebastine produces 1,2-dihydro-1,2-dihydroxyrotenone produces 1,2-dihydrorotenone produces 3-hydroxyrotenone produces acronine acronycine produces imipramine transforms alkaloids transforms flavonoids transforms pergolide oxidation of ebastine to carebastine transformation of sesquiterpene lactone costunolide transformation of: pergolide to pergolide sulfoxide |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | frozen |
| Storage Conditions： | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Type Strain： | no |
| Preceptrol®： | no |
| Mating Type： | mating type plus |
| Comments： | Comparable to Upjohn H-334 used in oxidation of steroids |
| Medium： | ATCC® Medium 200: YM agar or YM broth ATCC® Medium 307: Cornmeal agar ATCC® Medium 336: Potato dextrose agar (PDA) |
| Growth Conditions： | Temperature: 24°C to 26°C Atmosphere: Typical aerobic |
| Name of Depositor： | NRRL |
| Special Collection： | NSF - Mycology |
| References： | Sariaslani FS, Rosazza JP. Microbial transformations of natural antitumor agents: Products of rotenone and dihydrorotenone transformation by Cunninghamella blakesleeana. Appl. Environ. Microbiol. 45: 616-621, 1983. Ibrahim AR, Abul-Hajj YJ. Microbiological transformation of flavone and isoflavone. Xenobiotica 20: 363-373, 1990. PubMed: 2346033 Mann KM, et al. Studies on microbiological oxidation of steroids by Cunninghamella blakesleeana. Effect of alcohols and phenol. Appl Microbiol 3: 14, 1955. Schwartz H, et al. Microbial oxidation of ebastine. Appl. Microbiol. Biotechnol. 44: 731-735, 1996. PubMed: 8867630 Betts RE, et al. Microbial transformations of antitumor compounds. I. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata. J. Med. Chem. 17: 599-602, 1974. PubMed: 4829940 Clark AM, Hufford CD. Microbial transformations of the sesquiterpene lactone costunolide. J. Chem. Soc. Perkin Trans. 1979: 3022-3028, 1979. Hufford CD, et al. Metabolism of imipramine by microorganisms. J. Pharm. Sci. 70: 151-155, 1981. PubMed: 7205217 Reighard JB, et al. Microbial biotransformations. I. O-Demethylation of 7,8-dimethoxy-2-methyl-1-(4-methoxybenzyl) 1,2,3,4.-tetrahydroisoquinoline by Cunninghamella blakesleeana. J. Nat. Prod. 44: 466-469, 1981. Smith RV, et al. Microbial transformations of pergolide to pergolide sulfoxide and pergolide sulfone. J. Pharm. Sci. 72: 733-736, 1983. PubMed: 6684155 |