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微信小章| 产品名称： | Acremonium chrysogenum (Thirumalachar et Sukapure) Gams |
|---|---|
| 商品货号： | TS206021 |
| Deposited As： | Acremonium chrysogenum (Thirumalachar et Sukapure) Gams, anamorph |
| Strain Designations： | C-10 |
| Application： | produces 5-(2-aminoadipyl)cysteinylvaline synthetase ACV synthetase produces cephalosporin C produces deacetoxycephalosporin C synthetase produces isopenicillin N synthetase produces: 18,000 mcg/ml cephalosporins in a complex medium |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | freeze-dried |
| Type Strain： | no |
| Preceptrol®： | no |
| Comments： | Atypical |
| Medium： | ATCC® Medium 336: Potato dextrose agar (PDA) |
| Growth Conditions： | Temperature: 24.0°C |
| Name of Depositor： | J Lein |
| Cross References： | Nucleotide (GenBank) : AJ238108 Acremonium chrysogenum cah gene, exons 1-3. |
| References： | Hollander IJ, et al. A pure enzyme catalyzing penicillin biosynthesis. Science 224: 610-612, 1984. PubMed: 6546810 Shen YQ, et al. Levels of isopenicillin N synthase and deacetoxycephalosporin C synthase in Cephalosporium acremonium producing high and low levels of cephalosporin C. Bio-Technology 4: 61-64, 1986. Zhang J, et al. Carbon source regulation of ACV synthetase in Cephalosporium acremonium C-10. Curr. Microbiol. 18: 361-367, 1989. Malmberg LH, Hu WS. Identification of rate-limiting steps in cephalosporin C biosynthesis in Cephalosporium acremonium: a theoretical analysis. Appl. Microbiol. Biotechnol. 38: 122-128, 1992. PubMed: 1369008 Zhang J, Demain AL. Regulation of ACV synthetase activity in the beta-lactam biosynthetic pathway of carbon sources and their metabolites. Arch. Microbiol. 158: 364-369, 1992. Luengo JM, et al. Direct enzymatic synthesis of penicillin G using cyclases of Penicillium chrysogenum and Acremonium chrysogenum. Bio-Technology 4: 44-47, 1986. Shen YQ, et al. Desacetoxycephalosporin C synthetase: importance of order of cofactor/reactant addition. Enzyme Microb. Technol. 6: 402-404, 1984. |