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微信小章| 产品名称： | Cunninghamella elegans Lendner |
|---|---|
| 商品货号： | TS206059 |
| Deposited As： | Cunninghamella blakesleeana Lendner |
| Strain Designations： | 296 CBS 167.53, DSM 1908, DSM 835, IMI 314507, NRRL 2310 |
| Application： | hydrolyzes sclareol produces 9,10-dimethyl-1,2 benzanthracene 7,12-dimethylbenz-aanthracene produces acronine acronycine produces carbomycin derivatives magnamycin derivatives produces leucomycin derivatives produces niddamycin derivatives produces steroids transforms amoxapine transforms azatadine transforms brompheniramine transforms chlorpheniramine transforms chlorpromazine transforms methdilazine transforms pheniramine transforms solasodine transformation of: amoxapine to 7-hydroxyamoxapine transformation of: sesquiterpene lactone costunolide transformation of: pergolide to pergolide sulfoxide |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | frozen |
| Storage Conditions： | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Type Strain： | no |
| Preceptrol®： | no |
| Medium： | ATCC® Medium 200: YM agar or YM broth ATCC® Medium 323: Malt agar medium ATCC® Medium 336: Potato dextrose agar (PDA) |
| Growth Conditions： | Temperature: 24°C to 26°C Atmosphere: Typical aerobic |
| Sequenced Data： |
18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence GGTTTCCGTAGGTGAACCTGCGGAAGGATCATTACTTATTCGGTCATTGGTTTTTATTCAAAAACCTTTGGCTTTAAATCATCCACAGTGTGGGAAATGTCTTCTAACGCTTGTGCCTGGTTCAGTCTAGTGCTGCCACTTGAGTTTACTCTTGGGTCAAGGGACCTTTGGGTAGTTTGTTCATTCGTGAGCAACCTCTTGTAACGGGGATAAGATTAATTTTATTATACTAAATTTTACTGAACTGATAGACCATAAATCTATGGTTGTTTTTTATTATAAACAAAAAAACAACTTTCAGCAATGGATCTCTCGGCTTTCGTATCGATGAAGAACGCAGCAAATCGCGATATGTAATGTGATCTGCCTATAGTGAATCATCAAATCTTTGAACGCATCTTGCACCTTATGGTATTCCATAAGGTACGTCTGTTTCAGTACCACTAGTAAATCTCCCCTCCACCTTGGTGGTTTAAAAGGAAGAGATAAATTATTACTGGTTCTGGTGATTCTTGATTTATTAAGAATTACTCTCGACCTAAATATAAGGCTCGACTTTTTTATTAGATCTCGCATCTGGTAAAACCTAGTCGGCTTTAATAGGATTTATTTCTTATTAGGTTTATAGCCATCATTTTACTTTTAAATCTTGGCCTGAAATCAGATGGGACTACCCGCTGAACTTAAGCATATCAATAA D1D2 region of the 28S ribosomal RNA gene CATATCAATAAGCGGAGGAAAAGAAAATAACAATGATTCCCCTAGTAACGGCGAGTGAAGAGGGAAAAGCTCAAAGTTGGAACCTGGTGGGCATAGCTCACCCGGATTGTAAACTAAAGTTTTTGAGTCGTTTAGTCAGCCAGGTAAATAAGTCCTCTGGAAAGGGGCGACATAGAGGGTGAAATCCCCGTCTTTGGCCTGAGTTTTGGTTAGGCGTTTGGCTTGGAAACGAAGAGTCAGGTTGTTTGGGAATGCAGCCTAAAATGGGAGGTAAATCTCTCCTAAAGCTAAATATTGACGAAAGACCGATAGCGAACAAGTACCGTGAGGGAAAGATGAAAAGCACTTTGAAAAGAGGGTCAAAAAGTACGTGAAATTGCTGAAAGGGAACCGTATGAAATCAGACCTACTGGTAGGTAATCAATCTTTCCCTTGGGAAGGATGCACTTGCCTGCTATGTATGCCAGCGACATTTTGGTTGGGAGGAAAAAAATAGAAGGAATGTAGCCTAGGCTTCGGTTTAGGTGTTATAGACTTTTATAAAATACTCTCGGCTGGAATGAGGAACGCAGCAAACCGTAAGGCGAAGATTCTAGTCGCTTGGGGGGAATAATTAGAGAATTTCTGCTTCGGGTGGTGCTTTGATTATTACTTTCAACTCGGTTGGAGTTCTTTTAATTTGCTTAGGTTGTTGGCTTAATGATTTTATATGA |
| Name of Depositor： | VM Cutter |
| Isolation： | Flax seeds, Linum usitatissimum, Winkler, Manitoba, Canada |
| Cross References： | Nucleotide (GenBank) : M36310 Cunninghamella elegans 5S ribosomal RNA. |
| References： | Bloom BM, Shull GM. Epoxidation of unsaturated steroids by microorganisms. J. Am. Chem. Soc. 87: 5767-5768, 1965. Wong LK, et al. Metabolism of 7,12-dimethylbenzaanthracene by Cunninghamella elegans. Appl. Environ. Microbiol. 46: 1239-1242, 1983. PubMed: 6418073 Theriault RJ. Mycarosyl macrolide antibiotics. US Patent 3,784,447 dated Jan 8 1974 Wolf-Rainer A. Microbial hydroxylation of sclareol. Phytochemistry 36: 1421-1424, 1994. Zhang D, et al. Biotransformation of chlorpromazine and methdilazine by Cunninghamella elegans. Appl. Environ. Microbiol. 62: 798-803, 1996. PubMed: 8975609 Hansen EB Jr., et al. Fungal transformations of antihistamines: metabolism of brompheniramine, chlorpheniramine, and pheniramine to N-oxide and N- demethylated metabolites by the fungus Cunninghamella elegans. Xenobiotica 25: 1081-1092, 1995. PubMed: 8578764 Zhang D, et al. Fungal biotransformation of the antihistamine azatadine by Cunninghamella elegans. Appl. Environ. Microbiol. 62: 3477-3479, 1996. PubMed: 8795241 Moody JD, et al. Transformation of amoxapine by Cunninghamella elegans. Appl. Environ. Microbiol. 66: 3646-3649, 2000. PubMed: 10919836 Betts RE, et al. Microbial transformations of antitumor compounds. I. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata. J. Med. Chem. 17: 599-602, 1974. PubMed: 4829940 Clark AM, Hufford CD. Microbial transformations of the sesquiterpene lactone costunolide. J. Chem. Soc. Perkin Trans. 1979: 3022-3028, 1979. Smith RV, et al. Microbial transformations of pergolide to pergolide sulfoxide and pergolide sulfone. J. Pharm. Sci. 72: 733-736, 1983. PubMed: 6684155 Patel AV. Transformations of solasodine and derivatives of hecogenin by Cunninghamella elegans. Phytochemistry 35: 125-133, 1994. Walther G, et al. DNA barcoding in Mucorales: an inventory of biodiversity. Persoonia 30: 11-47, 2013. PubMed: 24027345 Vitale RG, et al. Antifungal susceptibility and phylogeny of opportunistic members of the order Mucorales. J Clin Microbiol 50: 66-75, 2012. PubMed: 22075600 |