| 产品名称: | Streptomyces argillaceus Routien |
|---|---|
| 商品货号: | TS208177 |
| Strain Designations: | 5576-27 |
| Application: | Produces plicamycin mithramycin Production of the tumor-inhibiting agents mithramycin A, B and/or C |
| Isolation: | Soil |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format: | freeze-dried |
| Disclosure: | This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC. |
| Preceptrol®: | no |
| Type Strain: | no |
| Medium: | ATCC® Medium 196: Yeast malt extract agar |
| Growth Conditions: | Temperature: 26.0°C |
| Name of Depositor: | Chas. Pfizer & Co., Inc. |
| U.S. Patent Number: | |
| References: | Sobin BA, et al. Mithramycins as transplanted tumor inhibiting agents. US Patent 3,646,194 dated Feb 29 1972 |
| Cross References: | Nucleotide (GenBank) : Y10907 S.argillaceus mtmD and mtmE genes. Nucleotide (GenBank) : AJ007932 Streptomyces argillaceus mithramycin biosynthetic genes. Nucleotide (GenBank) : X89899 S.argillaceus DNA for mtmQ, mtmX, mtmP, mtmK, mtmS and mtmT1 genes. Nucleotide (GenBank) : AF056309 Streptomyces argillaceus membrane protein and mithramycin regulator MtmR (mtmR) genes, complete cds. Nucleotide (GenBank) : AF056310 Streptomyces argillaceus sequence similar to the region upstream of the mithramycin regulatory gene. Nucleotide (GenBank) : U43537 Streptomyces argillaceus mithramycin resistance determinant, ATP-binding protein (mtrA) and membrane protein (mtrB) genes, complete cds. |