| 产品名称: | Streptomyces griseus subsp. griseus (Krainsky) Waksman and Henrici |
|---|---|
| 商品货号: | TS208986 |
| Strain Designations: | 4 BUCSAV 7, Boots FD40, NCIB 8232, NCTC 6961 |
| Application: | Produces cytochrome P450 and glutaminase.
Transformation of pergolide to pergolide sulfoxide and of 1,2-dihydrorotenone. |
| Isolation: | Derived from existing strain |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format: | freeze-dried |
| Storage Conditions: | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Preceptrol®: | yes |
| Type Strain: | no |
| Medium: | ATCC® Medium 1877: ISP Medium 1 ATCC® Medium 196: Yeast malt extract agar |
| Growth Conditions: | Temperature: 26°C Atmosphere: Aerobic |
| Name of Depositor: | SA Waksman |
| References: | Sariaslani FS, Rosazza JP. Biotransformations of 1,2-dihydrorotenone by Streptomyces griseus. Appl. Environ. Microbiol. 49: 451-452, 1985. PubMed: 3920966 Yokotsuka T, et al. Hydrolysis of glutamine within foods and beverages to glutamic acid. US Patent 3,717,470 dated Feb 20 1973 Proc. Soc. Exp. Biol. Med. 55: 66-69, 1944. Kunz DA, Sariaslani SF. Process for inducing cytochrome P-450 enzymes in Streptomyces bacteria and determining the mutagenicity of chemicals. US Patent 5,674,714 dated Oct 7 1997 Smith RV, et al. Microbial transformations of pergolide to pergolide sulfoxide and pergolide sulfone. J. Pharm. Sci. 72: 733-736, 1983. PubMed: 6684155 derived from Waksmans original streptomycin-producing strain 3463 |
| Cross References: | Nucleotide (GenBank) : X17368 S. griseus 5S rRNA. Nucleotide (GenBank) : X55551 S.griseus saf gene. Nucleotide (GenBank) : X74868 S.griseus gene for glutamic acid specific protease. Nucleotide (GenBank) : M64471 Streptomyces griseus (TS208986) trypsin (sprT) gene, complete cds. |