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微信小章| 产品名称： | Streptomyces avermitilis (ex Burg et al.) Kim and Goodfellow |
|---|---|
| 商品货号： | TS209269 |
| Deposited As： | Streptomyces avermitilis |
| Strain Designations： | NRRL 8165 JCM 5070, MA-4680, NCIMB 12804 |
| Application： | Produces avermectin avermectins, avermectin B(1)a C-076, and C-076 and derivatives. |
| Isolation： | Soil, Ito City, Shizuoka Pref., Japan |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | freeze-dried |
| Storage Conditions： | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Disclosure： | This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC. |
| Preceptrol®： | no |
| Genome Sequenced Strain： | Streptomyces avermitilis MA-4680 DNA, complete genome. |
| Type Strain： | yes |
| Comments： | Genome sequenced strain |
| Medium： | ATCC® Medium 184: Glucose asparagine agar |
| Growth Conditions： | Temperature: 26°C Atmosphere: Aerobic |
| Name of Depositor： | NRRL |
| U.S. Patent Number： | |
| Special Collection： | NSF - Bacteriology |
| Chain of Custody： | ATCC <-- NRRL <-- Merck & Co., Inc. MA-4680 |
| References： | Burg RW, et al. Avermectins, new family of potent anthelmintic agents: Producing organism and fermentation. Antimicrob. Agents Chemother. 15: 361-367, 1979. PubMed: 464561 Goegelman RT, et al. Novel C-076 compounds. US Patent 4,378,353 dated Mar 26 1983 Hafner EW, et al. Cultures for production of B avermectins. US Patent 5,565,359 dated Oct 15 1996 Ikeda H, et al. Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis. Nat. Biotechnol. 21: 526-531, 2003. PubMed: 12692562 Kim SB, Goodfellow M. Streptomyces avermitilis sp. nov., nom. rev., a taxonomic home for the avermectin-producing streptomycetes. Int. J. Syst. Evol. Microbiol. 52: 2011-2014, 2002. PubMed: 12508861 Miller TW, et al. Avermectins, new family of potent anthelmintic agents: Isolation and chromatographic properties. Antimicrob. Agents Chemother. 15: 368-371, 1979. PubMed: 464562 Ormond RE. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use. US Patent 4,412,991 dated Nov 1 1983 |
| Cross References： | Nucleotide (GenBank) : AY029771 Streptomyces avermitilis ribosomal protein S12 (rpsL) gene, complete cds. Nucleotide (GenBank) : BA000030 Streptomyces avermitilis MA-4680 DNA, complete genome. |