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微信小章| 产品名称： | Penicillium rubens Biourge |
|---|---|
| 商品货号： | TS209789 |
| Deposited As： | Penicillium chrysogenum Thom, anamorph |
| Strain Designations： | NRRL 1951 CBS 307.48, IMI 40233, QM 941, ATCC 28089 |
| Application： | Produces disulfide reductase
Produces ferrichrome
Produces penicillin
Transformation of sesquiterpene lactone costunolide
Produces antiviral agent consisting of double-stranded RNA |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | freeze-dried |
| Storage Conditions： | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Type Strain： | no |
| Preceptrol®： | no |
| Comments： | Prototype of high-yielding penicillin strains in submerged culture
Infected with mycoviruses
The strain was reclassified as Penicillium rubens based on a recent molecular phylogenetic study. Ref   Houbraken J, et al. New penicillin-producing Penicillium species and an overview of section Chrysogena. Persoonia 29: 78-100, 2012. PubMed: 23606767 |
| Medium： | ATCC® Medium 200: YM agar or YM broth ATCC® Medium 325: Malt extract agar (Blakeslees formula) ATCC® Medium 336: Potato dextrose agar (PDA) |
| Growth Conditions： | Temperature: 24°C to 26°C
Atmosphere: Typical aerobic |
| Sequenced Data： | No DNA sequencing was performed in house on this product.
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| Name of Depositor： | NRRL |
| Isolation： | Cantaloupe, Illinois |
| Cross References： | Nucleotide (GenBank) : X76119 thioredoxin reductase gene, trxB, partial sequence Nucleotide (GenBank) : X76120 thioredoxin reductase gene, trxA, partial sequence Nucleotide (GenBank) : AH004545 3-phosphoglycerate kinase gene, pgkA, partial sequence Nucleotide (GenBank) : D13859 mitochondrion genes for rRNA, tRNA, and 5S ribosomal protein, complete coding sequences |
| References： | Charlang G, et al. Cellular and extracellular siderophores of Aspergillus nidulans and Penicillium chrysogenum. Mol. Cell. Biol. 1: 94-100, 1981. PubMed: 6242827 Mateos RC, Sanchez S. Transport of neutral amino acids and penicillin formation in Penicillium chrysogenum. J. Gen. Microbiol. 136: 1713-1716, 1990. Sutherland ES, et al. Production of double stranded ribonucleic acid. US Patent 3,597,318 dated Aug 3 1971 Lemke PA, Ness TM. Isolation and characterization of a double-stranded ribonucleic acid from Penicillium chrysogenum. J. Virol. 6: 813-819, 1970. PubMed: 4322084 Cohen G, et al. The thioredoxin system of Penicillium chrysogenum and its possible role in penicillin biosynthesis. J. Bacteriol. 176: 973-984, 1994. PubMed: 8106340 Hoskins IC, Roberts CF. Expression of the 3-phosphoglycerate kinase gene (pgkA) of Penicillium chrysogenum. Mol. Gen. Genet. 243: 270-276, 1994. PubMed: 8190080 Naruse A, et al. Nucleotide sequence of the large mitochondrial rRNA gene of Penicillium chrysogenum. Biochim. Biophys. Acta 1172: 353-356, 1993. PubMed: 7680578 Clark AM, Hufford CD. Microbial transformations of the sesquiterpene lactone costunolide. J. Chem. Soc. Perkin Trans. 1979: 3022-3028, 1979. Houbraken J, et al. New penicillin-producing Penicillium species and an overview of section Chrysogena. Persoonia 29: 78-100, 2012. PubMed: 23606767 |