| 产品名称: | Acremonium chrysogenum (Thirumalachar et Sukapure) Gams |
|---|---|
| 商品货号: | TS209794 |
| Deposited As: | Acremonium chrysogenum (Thirumalachar et Sukapure) Gams, anamorph |
| Strain Designations: | CBS 779.69, DSM 880, IMI 49137 |
| Application: | Degrades cassava
Produces alkaline protease
Produces cephalosporin C
Produces cephalosporin P
Produces deacetoxycephalosporin C
Produces penicillin N adicillin, cephalosporin N, isopenicillin N, synnematin B
Produces protease nonstructural protein 3
Produces single-cell protein SCP
Transformation host
Produces single-cell protein from cassava
Transformation host for expression of Fusarium alkaline protease gene |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format: | freeze-dried |
| Storage Conditions: | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Type Strain: | no |
| Preceptrol®: | no |
| Genome Sequenced Strain: | Yes |
| Comments: | Taxonomy
Virus-like particles
Polymorphic karyotype
Genome sequencing strain (China state institute of pharmaceutical industry, China; Ruhr-Universitaet Bochum, Germany) |
| Medium: | ATCC® Medium 200: YM agar or YM broth ATCC® Medium 335: Potato carrot agar ATCC® Medium 336: Potato dextrose agar (PDA) |
| Growth Conditions: | Temperature: 24°C to 26°C
Atmosphere: Typical aerobic |
| Sequenced Data: | No DNA sequencing was performed in house on this product.
|
| Name of Depositor: | NG Heatley |
| U.S. Patent Number: | 3,979,260 |
| Chain of Custody: | ATCC <-- NG Heatley <-- G. Brotzu (Cephalosporium chrysogenum) |
| Isolation: | Seawater, Sardinia, Italy |
| Cross References: | Nucleotide (GenBank) : X82163 A.chrysogenum ACP1 promoter DNA. Nucleotide (GenBank) : X82164 A.chrysogenum ACP2 promoter DNA. Nucleotide (GenBank) : U17426 Acremonium chrysogenum large subunit ribosomal RNA, partial Nucleotide (GenBank) : X15937 Cephalosporium acremonium pyr4 gene for orotidine-5-phosphate Nucleotide (GenBank) : JPKY00000000 Acremonium chrysogenum TS209794, whole genome shotgun sequencing project |
| References: | Terfehr D, et al. Genome sequence and annotation of Acremonium chrysogenum, producer of the beta-lactam antibiotic cephalosporin C. Genome Announc 2(5). pii: e00948-14, 2014. PubMed: 25291769 Gsaller F, et al. The first promoter for conditional gene expression in Acremonium chrysogenum: iron starvation-inducible mir1(P). J Biotechnol 163: 77-80, 2013. PubMed: 23089729 Morita S, et al. Secretion of active human lysozyme by Acremonium chrysogenum using a Fusarium alkaline protease promoter system. J. Biotechnol. 42: 1-8, 1995. PubMed: 7662338 Morita S, et al. High level expression of Fusarium alkaline protease gene in Acremonium chrysogenum. Biosci. Biotechnol. Biochem. 58: 627-630, 1994. PubMed: 7764854 Walz M, Kuck U. Polymorphic karyotypes in related Acremonium strains. Curr Genet 19: 73-76, 1991. PubMed: 1676616 Isogai T, et al. Cloning and nucleotide sequences of the complementary and genomic DNAs for the alkaline protease from Acremonium chrysogenum. Agric. Biol. Chem. 55: 471-477, 1991. PubMed: 1368696 Hoskins JA, et al. Gene disruption of the pcbAB gene encoding ACV synthetase in Cephalosporium acremonium. Curr. Genet. 18: 523-530, 1990. PubMed: 2076552 Gregory KF. Feed enrichment with microbial protein. Conserv. Recycl. 5: 33-40, 1982. Kitano K, Kintaka K, Nakao Y. Comparative study of methionine effect on cephalosporin production by various fungi. J Ferment Technol 55: 27-36, 1977. Day LE, Ellis LF. Virus-like particles in Cephalosporium acremonium. Appl. Microbiol. 22: 919-920, 1971. PubMed: 4108900 Yagi J, et al. Studies on alkaline proteinase from Cephalosporium. I. Purification of the enzyme. J. Ferment. Technol. 50: 592-599, 1972. Yagi J, et al. Alkaline proteinase from Cephalosporium sp. II. Enzymatic properties of the alkaline proteinase. J. Ferment. Technol. 50: 810-815, 1972. Yagi J, et al. Alkaline proteinase from Cephalosporium sp. III. Physiochemical properties of the enzyme. J. Ferment. Technol. 50: 816-822, 1972. Yagi J, et al. Production of protease by Cephalosporium sp. in a pilot plant. J. Ferment. Technol. 53: 99-102, 1975. Nakao Y, et al. Production of deacetoxycephalosporin C. US Patent 3,979,260 dated Sep 7 1976 |