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微信小章| 产品名称： | Acremonium chrysogenum (Thirumalachar et Sukapure) Gams |
|---|---|
| 商品货号： | TS209796 |
| Deposited As： | Cephalosporium sp. |
| Strain Designations： | 8650 |
| Application： | produces cephalosporin C produces cephalosporins produces deacetoxycephalosporin C produces penicillin transformation host produces: arthospore-inducing substances for production of cephalosporin C |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | freeze-dried |
| Type Strain： | no |
| Disclosure： | This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC. |
| Preceptrol®： | no |
| Comments： | transformation using a vector without bacterial DNA Carries plasmid pAC1 for preparing a hybrid vector which promotes the biosynthesis of beta-lactam antibiotics polymorphic karyotype |
| Medium： | ATCC® Medium 335: Potato carrot agar |
| Growth Conditions： | Temperature: 24.0°C |
| Name of Depositor： | RC Godner |
| U.S. Patent Number： | |
| Isolation： | Mutant of ATCC 11550 |
| Cross References： | Nucleotide (GenBank) : X72789 beta-tubulin gene |
| References： | Kelly BK, et al. Production of cephalosporin C. US Patent 3,082,155 dated Mar 19 1963 Nakao Y, et al. Production of deacetoxycephalosporin C. US Patent 3,979,260 dated Sep 7 1976 Katamoto K, et al. Method for separating cephalosporins. US Patent 4,535,155 dated Aug 13 1985 Esser K, Minuth W. Plasmid pAC 1, a process for obtaining it and its use. US Patent 4,506,014 dated Mar 19 1985 Walz M, Kuck U. Polymorphic karyotypes in related Acremonium strains. Curr Genet 19: 73-76, 1991. PubMed: 1676616 Nowak C, Kuck U. Development of an homologous transformation system for Acremonium chrysogenum based on the beta-tubulin gene. Curr. Genet. 25: 34-40, 1994. PubMed: 8082163 Menne S, et al. Expression studies with the bidirectional pcbAB-pcbC promoter region from Acremonium chrysogenum using reporter gene fusions. Appl. Microbiol. Biotechnol. 42: 57-66, 1994. PubMed: 7765820 Nowak C, et al. DNA-mediated transformation of a fungus employing a vector devoid of bacterial DNA sequences. Appl. Microbiol. Biotechnol. 43: 1077-1081, 1995. PubMed: 8590659 Shirafuji H, et al. Accumulation of tripeptide derivatives by mutants of Cephalosporium acremonium. Agric. Biol. Chem. 43: 155-160, 1979. Natsume M, Marumo S. Arthrospore-inducing substances from Acremonium chrysogenum which stimulate cephalosporin C production. Agric. Biol. Chem. 48: 567-569, 1984. Huber FM, Redstone MO. Changes in the fatty acids of Cephalosporium acremonium Corda and its growth medium. Can. J. Microbiol. 13: 332-334, 1969. Lemke PA, Nash CH. Mutations that affect antibiotic synthesis by Cephalosporium acremonium. Can. J. Microbiol. 18: 255-259, 1972. PubMed: 4336241 Queener SW, et al. Glutamate dehydrogenase specific activity and cephalosporin C synthesis in the M8650 series of Cephalosporium acremonium mutants. Antimicrob. Agents Chemother. 7: 646-651, 1975. PubMed: 1170808 |