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微信小章| 产品名称： | GB virus B |
|---|---|
| 商品货号： | TS213400 |
| Classification： | Flaviviridae |
| Deposited As： | Hepatitis virus (unclassified) |
| Agent： | GB virus B |
| Strain： | GB |
| Biosafety Level： | 2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Isolation： | Agent detected in tamarins injected with acute phase serum from a human male with viral hepatitis |
| Product Format： | frozen 1 mL per vial |
| Storage Conditions： | -70°C or colder |
| Comments： | Originally believed to be a human virus but now assumed to be a tamarin virus
Infectivity stable at 50°C for 30 minutes (partially inactivated at 60°C for 1 hour).
The GB agent is distinct from hepatitis A and B. The GB isolate may have two components (GB-A & GB-B).
It is different from the MS-1, reference hepatitis A strain. Originally believed to be a human hepatitis.
The vial contains acute phase serum from tamarin monkeys infected with the virus |
| Effect on Host： | Enzymatic and histologically typical viral hepatitis |
| Recommended Host： | Saguinus mystax (moustached tamarin) |
| Growth Conditions： | Incubation:xa014-28 days |
| Name of Depositor： | F Deinhardt |
| Source： | Agent detected in tamarins injected with acute phase serum from a human male with viral hepatitis |
| References： | Deinhardt F, et al. Studies on the transmission of human viral hepatitis to marmoset monkeys. I. Transmission of disease, serial passages, and description of liver lesions. J. Exp. Med. 125: 673-688, 1967. PubMed: 4960092 Deinhardt F, et al. Hepatitis in marmosets. Am. J. Med. Sci. 270: 73-80, 1975. PubMed: 171953 Beames B, et al. Development of a primary tamarin hepatocyte culture system for GB virus-B: a surrogate model for hepatitis C virus. J. Virol. 74: 11764-11772, 2000. PubMed: 11090176 Simons JN, et al. Identification of two flavivirus-like genomes in the GB hepatitis agent. Proc. Natl. Acad. Sci. USA 92: 3401-3405, 1995. PubMed: 7724574 |