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| 产品名称： | Simian virus 40 |
|---|---|
| 商品货号： | TS213494 |
| Classification： | Polyomaviridae, Polyomavirus |
| Deposited As： | Sv-40 pml-2 |
| Agent： | Simian virus 40 |
| Strain： | DAR |
| Common Name： | Simian virus 40 |
| Applications： | Neutralized by anti SV-40 serum, but in reciprocal kinetic neutralization tests differences in K values were noted when compared to SV-40. Neutralized by commercial anti SV-40 serum, but in reciprocal kinetic neutralization tests differences in K values were noted when compared to SV-40. |
| Biosafety Level： | 2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Isolation： | human brain homogenate of female patient with progressive multifocal leukoencephalopathy, 1971 |
| Product Format： | freeze-dried |
| Storage Conditions： | xa0-70°C or colder |
| Comments： | Neutralized by anti SV-40 serum, but in reciprocal kinetic neutralization tests differences in K values were noted when compared to SV-40. Resistant to treatment with chloroform, low pH, and 50C for 120 min. Neutralized by commercial anti SV-40 serum, but in reciprocal kinetic neutralization tests differences in K values were noted when compared to SV-40. |
| Effect on Host： | Yes, in vitro effects: Cytopathic effects in tissue culture (SV-40 like plaques) |
| Recommended Host： | BS-C-1 cells (ATCC CCL-26) Recommended Host: xa0BS-C-1 (ATCC® CCL-26x99) BS-C-1 cells (ATCC CCL-26); primary African green monkey kidney cells in tissue culture |
| Growth Conditions： | Duration: 7-10 days |
| Name of Depositor： | O Narayan |
| Source： | human brain homogenate of female patient with progressive multifocal leukoencephalopathy, 1971 |
| Year of Origin： | 1971 |
| References： | Weiner LP, et al. Isolation of virus related to SV40 from patients with progressive multifocal leukoencephalopathy. N. Engl. J. Med. 286: 385-390, 1972. PubMed: 4333082 Narayan O, Weiner LP. Biological properties of two strains of Simian virus 40 isolated from patients with progressive multifocal leukoencephalopathy. Infect. Immun. 10: 173-179, 1974. PubMed: 4367120 |