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| 产品名称： | Mouse mammary tumor virus |
|---|---|
| 商品货号： | TS213574 |
| Classification： | Retrovirus, Mammalian Type B Oncovirus |
| Agent： | Mouse mammary tumor virus |
| Strain： | GR |
| Applications： | Transfer infected cells once a week at 1:6 ratio; peak virus production occurs 48-72 hours after transfer. |
| Biosafety Level： | 2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Isolation： | This persistently infected cell line was established from an excised mammary tumor (adenocarcinoma) of a GR mouse, 1972 |
| Product Format： | frozen |
| Storage Conditions： | Liquid nitrogen |
| Comments： | The GR mammary tumors appear in infected GR mice during pregnancy and disappear at the end of pregnancy. Transfer infected cells once a week at 1:6 ratio; peak virus production occurs 48-72 hours after transfer. |
| Effect on Host： | No, in vitro effects: cytopathic effects in tissue culture Yes, tumorigenicity: produces hyperplastic alveolar nodules, plaques and mammary tumors in mice under suitable hormonal conditions |
| Recommended Host： | mouse mouse; mouse in tissue culture |
| Growth Conditions： | Incubation: 2-3 days |
| Name of Depositor： | EY Lasfargues |
| Special Collection： | ATCC |
| Source： | This persistently infected cell line was established from an excised mammary tumor (adenocarcinoma) of a GR mouse, 1972 |
| Year of Origin： | 1972 |
| References： | Muhlbock O. Note on a new inbred mouse-strain GR-A. Eur. J. Cancer 1: 123-124, 1965. PubMed: 5874925 Ringold G, et al. Production of mouse mammary tumor virus by cultured cells in the absence and presence of hormones: assay by molecular hybridization. Virology 65: 135-147, 1975. PubMed: 49975 Lasfargues E. . J. Cell Biol. 59: 187a and 373, 1973. |