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| 产品名称： | Avian coronavirus |
|---|---|
| 商品货号： | TS213698 |
| Classification： | Coronaviridae, Gammacoronavirus |
| Agent： | Avian coronavirus |
| Strain： | M41 |
| Common Name： | Infectious bronchitis virus (IBV) |
| Applications： | Unlike fully egg-adapted strains that are non-immunogenic, this strain produces satisfactory immunity as determined by neutralization test for antibodies. |
| Biosafety Level： | 2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | frozen |
| Storage Conditions： | xa0-70°C or colder |
| Comments： | The M41 (Massachusetts Michigan State University Repository Code 41) strain is the protype strain of IBV, however it should be noted that antigenicity and virulence of IBV change readily with passage in culture. Unlike fully egg-adapted strains that are non-immunogenic, this strain produces satisfactory immunity as determined by neutralization test for antibodies. |
| Effect on Host： | Yes, in vivo effects: curling, stunting and pale coloring of infected embryos or chickens; may cause death. |
| Recommended Host： | Production Host: Embryonated chicken egg (9 to 10-day old). Recommended Host: xa0Embryonated chicken egg (9 to 10 day old) Alternate Host: Chicken (10-day old, intratracheal inoculation). |
| Growth Conditions： | Temperature: 37.0°C Recommendations for Infection: Inoculate embryonated chicken eggs (9 to 10-day old) by the allantoic cavity route with 0.2 mL of a 1:10 to 1:100 dilution of virus in DPBS. Incubation: 2-6 days |
| Name of Depositor： | CH Cunningham, Michigan State University |
| Special Collection： | ATCC |
| Chain of Custody： | Deposited as Infectious bronchitis virus |
| Source： | Isolated in 1941 from 19-day old chicks accidentally infected in the laboratory, University of Massachusetts. |
| References： | Cunningham CH. Symposium on immunization against infectious bronchitis virus. I. Some basic properties of infectious bronchitis virus. Am. J. Vet. Res. 18: 648, 1957. PubMed: 13444588 Cunningham CH. . Adv. Vet. Sci. 14: 106-148, 1970. McIntosh K. . Curr. Top. Microbiol. Immunol. 63: 86-119, 1974. Cunningham CH. . Am. J. Vet. Res. 21: 498, 1960. |