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| 产品名称： | Murine leukemia virus |
|---|---|
| 商品货号： | TS213753 |
| Classification： | Retroviridae, Gammaretrovirus, Mammalian virus group |
| Agent： | Murine leukemia virus |
| Strain： | 292A |
| Applications： | Does not produce plaques in XC assay. |
| Positive for Mycoplasma： | Yes |
| Biosafety Level： | 2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Isolation： | Pool of spinal cord extracts from naturally paralyzed wild mice, Lake Casitas |
| Product Format： | frozen |
| Storage Conditions： | -70°C or colder |
| Comments： | Typical type C retrovirus. Amphotropic. Not identical to dual-tropic agents isolated from pre-leukemic mice. Does not produce plaques in XC assay. This item has tested positive for mycoplasma by PCR but not by culture. |
| Effect on Host： | No, in vitro effects: Cytopathic effects in SC-1 cells Paralysis and lymphoma in mice; induces plaques ringed by clusters of dead cells in PG-4 (ATCC® CRL-2032x99); no CPE in SC-1. Yes, in vitro effects: induces plaques ringed by clusters of dead cells in PG4 (feline S+L-) in tissue culture Yes, in vivo effects: paralysis and lymphoma in mice |
| Recommended Host： |
Homo sapiens
human
Felis catus
cat Recommended Host:xa0 M. duniixa0 (ATCC® CRL-2017x99) |
| Growth Conditions： | Duration: Variable; temperature 37C |
| Name of Depositor： | M Gardner |
| Source： | Pool of spinal cord extracts from naturally paralyzed wild mice, Lake Casitas |
| References： | Rasheed S, et al. Amphotropic host range of naturally occuring wild mouse leukemia viruses. J. Virol. 19: 13-18, 1976. PubMed: 181592 The preferred intact host is an Fv-1 n mouse. |