| 产品名称: | p559 |
|---|---|
| 商品货号: | TS214110 |
| Designations: | p559 |
| Species: | Homo sapiens, human |
| Vector: | Construct size (kb): 4.400000095367432 |
| Insert: | DNA: cDNA Insert lengths(kb): 1.399999976158142 Tissue: retina Gene product: choroideremia(REP-1, Rab escort protein 1, tapeto-choroidal dystrophy, progressive choroidemia) CHM |
| Insert Size (kb): | 1.400 |
| Biosafety Level: | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information: | Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng) |
| Comments: | Restriction digests of the clone give the following sizes (kb): EcoRI/HindIII--2.8, 0.80, 0.70; BamHI--4.4; BglII--4.4; EcoRI--3.5, 0.86; HindIII--4.4. The insert contains the following restriction sites (approximate kb from the 5 end): PstI--0.28; BglII--0.47, 0.5; EcoRI--0.75; AccI--1.12. The insert is not cut with HindIII, BamHI, XbaI, SalI, or HincII. Detects 9 exons contained in human genomic EcoRI fragments of the following sizes (kb, 5 to 3): 7.5 (contains 3 exons), 4.5 or 4.2, 12.5, 2.6, 4.0, 1.0, 7.0. Corresponds to the 5 EcoRI/NcoI fragment of T8. Transcription from the SP6 and T7 promoters give the sense and antisense strands, respectively. |
| References: | Cremers FP, et al. Cloning of a gene that is rearranged in patients with chroideraemia. Nature 347: 674-677, 1990. PubMed: 2215697 Frans P Cremers, personal communication |