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| NCIMB number | NCIMB 8594 |
| Deposit type | Bacteria |
| Type strain | Yes |
| GMO | No |
| Taxon name | Saccharopolyspora erythraea |
| Depositor designation | McGuireM5-12559 Boots903 |
| Preservation method | Lyophilised |
| Preserved as | Streptomyces erythraeus |
| Price band | A |
| Media | 029 |
| Gas regime | aerobic |
| Growth factors (and/or information) | S. niveus, 30C, 1wk: poor growth, vegetative - buff, slow growing 2wk to produce aer. mycel., veg. greenish in first weed reverting to buff with aer. |
| ACDP category | 1 |
| Additional hazard information | Not known to cause infections but inhalation of spores may cause respiratory allergies in sensitised individuals. |
| Colony Edge | Entire |
| Colony Shape | Circular |
| Colony Elevation | Convex |
| Colony Colour | Off White |
| Colony Opacity | Opaque |
| Cellular Shape | Branching Hyphae |
| Depositor Company | American Type Culture Collection (ATCC) |
| Depositor Address | 12301 Parklawn Drive Rockville Maryland 20852 U.S.A. |
| Source | "Soil, Philippines" |
| Date of Accession | 01/03/1954 |
| History | Eli Lilly & Co. |
| Other collection IDs | ATCC11635 CBS727.72 DSM40517 ETH14307 ETH28360 ETH28344 ETH28391 HUT6087 IAM0045 IFO13426 IMRU3737 ISP5517 JCM4026 JCM4748 KCCS-0026 KCCS-0748 NRRL2338 RIA1387 |
| Yeast? | False |
| K12 | No |
| References | US Patent 2 653 899 Waksman S.A. and Curtis R.E. (1916) Soil Science 1 p99 Waksman S.A. (1919) Soil Science 8 p112 McGuire J.M. et al (1952) Antibiotics and Chemotherapy 2 p281 J. Am. Chem. Soc. (1954) 76 p569 Corum C.J. et al (1954) Appl. Microbiol. 2 p326 Ettlinger L. et al (1958) Arch. Mikrobiol. 31 p326 Hutter R. et al (1961) Arch. Mikrobiol. 39 p158 (Unknown); Actinomycetologica 6, 79-90, 1992; , Conserved indels in protein sequences that are characteristic of the phylum Actinobacteria; Int J Syst Evol Microbiol 55(6), 2401-2412, 2005; , The tmRNA website: reductive evolution of tmRNA in plastids and other endosymbionts; Nucleic Acids Res 32(Databaseissue), D104-D108, 2004; , Unification of the genera Streptoverticillium and Streptomyces, and amendation of Streptomyces Waksman and Henrici 1943, 339 AL; Syst Appl Microbiol 13, 361-371, 1990; , A repeated decapeptide motif in the C-terminal domain of the ribosomal RNA methyltransferase from the erythromycin producer Saccharopolyspora erythraea; FEBS Lett 262(2), 189-193, 1990; , An erythromycin derivative produced by targeted gene disruption in Saccharopolyspora erythraea; Science 252(5002), 114-117, 1991; , An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea; Nature 348(6297), 176-178, 1990; , Analysis of an 8.1-kb DNA fragment contiguous with the erythromycin gene cluster of Saccharopolyspora erythraea in the eryCI-flanking region; Antimicrob Agents Chemother 46(12), 3892-3899, 2002; , Analysis of eryBI, eryBIII and eryBVII from the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea; Mol Gen Genet 258(1-2), 78-88, 1998; , Analysis of seven genes from the eryAI-eryK region of the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea; Mol Gen Genet 256(3), 239-251, 1997; , Characterization of Saccharopolyspora erythraea cytochrome P-450 genes and enzymes, including 6-deoxyerythronolide B hydroxylase; J Bacteriol 174(3), 725-735, 1992; , Characterization of the genes and attachment sites for site-specific integration of plasmid pSE101 in Saccharopolyspora erythraea and Streptomyces lividans; Mol Gen Genet 242(2), 185-193, 1994; , Cloning of the genes encoding thymidine diphosphoglucose 4,6-dehydratase and thymidine diphospho-4-keto-6-deoxyglucose 3,5-epimerase from the erythromycin-producing Saccharopolyspora erythraea; Gene 153(1), 33-40, 1995; , Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338; Nat Biotechnol 25(4), 447-453, 2007; , Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338; Nature Biotech 25(4), 447-453, 2007; , Disruption of a rhodaneselike gene results in cysteine auxotrophy in Saccharopolyspora erythraea; J Bacteriol 172(1), 350-360, 1990; , Erythromycin production in Saccharopolyspora erythraea does not require a functional propionyl-CoA carboxylase; Mol Microbiol 19(5), 977-984, 1996; , Genetic approach for the fast discovery of phenazine producing bacteria; Mar Drugs 9(5), 772-789, 2011; , GtRNAdb: a database of transfer RNA genes detected in genomic sequence; Nucleic Acids Res 37(Databaseissue), D93-D97, 2009; , Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis; J Bacteriol 175(1), 182-189, 1993; , IS1136, an insertion element in the erythromycin gene cluster of Saccharopolyspora erythraea; Gene 126(1), 147-151, 1993; , Microbial conversion of avermectins by Saccharopolyspora erythraea: hydroxylation at C-27; J Antibiot (Tokyo) 47(3), 372-375, 1994; , Microbial conversion of avermectins by Saccharopolyspora erythrea: hydroxylation at C28; J Antibiot (Tokyo) 46(6), 1016-1019, 1993; , Nucleotide sequence of the ermE distal flank of the erythromycin biosynthesis cluster in Saccharopolyspora erythraea; Gene 193(1), 65-71, 1997; , Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production; Microbiology 143 ( Pt 10), 3251-3262, 1997; , |